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Forecast to Publish a Funding Opportunity Announcement for Limited Competition for the Continuation of the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) Research Project Sites (U01 Clinical Trials Optional)

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The National Institute on Alcohol Abuse and Alcoholism (NIAAA) is preparing to issue a funding opportunity announcement for a limited competition to continue the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) research project. Established in 2012, NCANDA investigates how adolescent alcohol use disrupts normal brain development, affecting brain structure, function, and psychiatric health into adulthood. The consortium has collected longitudinal data on over 800 individuals aged 12 to 32, capturing critical developmental stages from pre-drinking through young adulthood and the typical period of binge drinking. This dataset uniquely informs the long-term and short-term consequences of adolescent alcohol consumption on adult brain and behavior, offering insights unavailable in current adult-focused studies. The anticipated renewal will extend participant follow-up to age 37, enabling researchers to analyze how early versus late adolescent drinking impacts adult alcohol use and related behaviors. Findings from this work are expected to inform evidence-based prevention and early intervention strategies aimed at reducing severe drinking, alcohol use disorder progression, and associated chronic disease. The funding will use the U01 cooperative agreement mechanism, with the goal of supporting collaborative projects from investigators specializing in developmental neuroscience. Although applications are not yet being solicited, potential applicants are encouraged to prepare for submission once the announcement is published.

General Info

NIAAA to fund NCANDA renewal studying adolescent alcohol effects on brain development through age 37.

Agency

Department Of Health And Human Services → National Institutes Of Health

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology) View NAICS

Place of Performance

Not specified

Set-Aside

NONE

Documents

(0)

No documents available

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Timeline

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health
Contacts1 person available
OfficeUS
Organization / Agency
Department Of Health And Human Services → National Institutes Of Health
Office AddressUS
Contacts
Dominique Lorang-Leins National Institute on Alcohol Abuse and Alcoholism (NIAAA
contact@example.gov
+1 (555) 000-0000

Full Description

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The National Institute on Alcohol Abuse and Alcoholism (NIAAA) launched the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) in 2012 to determine how adolescent alcohol-related disruption of normal brain growth patterns of structure, related brain function, and psychiatric health affects brain functioning in emerging adulthood. The consortium uses an accelerated longitudinal design and has acquired data on over 800 individuals between the ages of 12 to 32 years. This wide age range covers the period before onset of drinking, the transition from adolescence to young adulthood, the critical period for binge drinking, and the time of maturing out. This unique dataset provides novel information on the enduring and transient consequences of adolescent drinking on adult brain function and behavior. Current studies on adults drinking do not have this type of data. Renewal of this limited competition NOFO will enable NCANDA to continue to follow these participants up to 37 years of age and acquire data critical to understanding how early versus late onset drinking during adolescence differentially impacts drinking behavior in adulthood. This limited competition renewal will provide valuable information for developing evidence-based alcohol prevention strategies and early intervention approaches to prevent the progression to more severe drinking and AUD thereby preventing the development of chronic disease, improving health outcomes, and increasing quality of life and longevity. Applications are not being solicited at this time. This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the U01 activity code. Investigators with expertise and insights into this area of developmental neuroscience are encouraged to begin to consider applying for this new NOFO. 

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