Forecast to Publish a Notice of Funding Opportunity (NOFO) for NCI Community Oncology Research Program (NCORP) Research Bases (UG1 Clinical Trial Required)
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Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.
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The National Cancer Institute (NCI) Community Oncology Research Program (NCORP) is issuing a Notice of Funding Opportunity (NOFO) to support NCORP Research Bases, which function as research hubs within the NCORP network. These Research Bases are responsible for leading multi-institutional clinical research focused on cancer control, prevention, and care delivery, as well as quality-of-life studies. Awardees will provide scientific and statistical leadership, oversee study operations and data management, ensure regulatory compliance, and support community and minority/underserved sites. Institutions with comprehensive expertise in cancer clinical research, such as cancer foundations or NCI-designated Cancer Centers, are expected to serve as Research Bases, integrating health disparities considerations into their work. The funded Research Bases must engage in cancer control research as a core focus area, with cancer prevention and cancer care delivery research as optional additional areas. The goal is to enhance the generalizability and dissemination of clinical trial outcomes by involving diverse community settings and patient populations, including those at risk for cancer. This funding opportunity facilitates rigorous studies aimed at improving cancer outcomes through prevention, control strategies, and optimized care delivery, strengthening partnerships across research institutions and community sites nationwide. The opportunity is posted by the National Institutes of Health and interested parties can contact the designated NCI representative for more information.
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Full Description
This Notice of Funding Opportunity (NOFO) is one of three NOFOs for the National Cancer Institute (NCI) Community Oncology Research Program (NCORP). NCORP is designed to enhance generalizability and dissemination of clinical trial results through accrual in a variety of community settings. The purpose of NCORP is to engage cancer patient populations, those at risk of cancer, and organizations in rigorous studies focused on cancer control, prevention, treatment and care delivery.
NCORP will support the following components that will be individually awarded through the respective Request for Applications (RFAs) indicated below:
- NCORP Research Bases (UG1 Clinical Trials Required);
- NCORP Community Sites (UG1 Clinical Trials Not Allowed); and
- NCORP Academic Community Sites (UG1 Clinical Trials Not Allowed)
NCORP Research Bases will serve as research hubs for the NCORP network. Research Bases are expected to:
- Provide an established organizational structure, with scientific and statistical leadership for developing, implementing, and analyzing multi-institutional cancer control, prevention, and care delivery (CCP&CD) clinical research, as well as quality-of-life studies embedded within treatment and imaging studies.
- Assume responsibility for study operations and data management, including efficient protocol development, compliance with Food and Drug Administration (FDA) and Office of Human Research Protections (OHRP) regulatory and participant protection requirements, audits, training, quality assurance, and support to Community Sites and Minority/Underserved Community Sites.
- Conduct their research activities at an institution with comprehensive expertise in cancer clinical research, such as a cancer foundation, healthcare research organization (including NCI's National Clinical Trials Network Group Operations Centers), or NCI-designated Cancer Center.
- Integrate health disparities across all focus areas as appropriate.
The scope of research activities for the proposed NCORP Research Bases encompasses three major areas delineated below:
Area 1: Cancer Control Research; and/or
Area 2: Cancer Prevention Research; and
Area 3: Cancer Care Delivery Research.
Research Bases must cover Area 1. Areas 2 and 3 are optional.
