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Funding Opportunity Announcement for Impact of Environmental Exposures on Gut-Brain Signaling in Neurological Conditions (R01)

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The National Institute of Environmental Health Sciences is planning to release a Notice of Funding Opportunity under the R01 activity code to support research on the gut microbiome-brain axis. The program aims to identify improved detection, prevention, and intervention strategies for neurological diseases induced by environmental exposures. This includes a broad scope of outcomes such as mental health disorders and chronic neurodegenerative conditions like Alzheimer’s and Parkinson’s disease. The primary objective is to develop gut-focused interventions, including probiotics, nutritional supplements, microbial biomarkers, and novel therapeutics, to reduce risk or slow the progression of these conditions. While applications are not yet being accepted, the agency is encouraging investigators with expertise in toxicology, neuroscience, and the microbiome to form collaborative partnerships in preparation for the upcoming solicitation.

General Info

NIEHS plans R01 funding for gut microbiome-brain research on environmental neurological diseases.

Agency

Department Of Health And Human Services → National Institutes Of Health

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

Place of Performance

Not specified

Set-Aside

NONE

Documents

0

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health
Contacts1 person available
OfficeUSA
Organization / AgencyDepartment Of Health And Human Services → National Institutes Of Health
Office AddressUSA
Contacts
Anika L. Dzierlenga Ph.D. National Institute of Environmental Health Sciences (NIEHS
contact@example.gov
+1 (555) 000-0000

Full Description

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The National Institute of Environmental Health Sciences (NIEHS) intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for research that builds on our understanding of the gut microbiome-brain axis for the purpose of identifying improved detection, prevention, and intervention strategies for environmental exposure-induced neurological diseases. Given the overlapping gut-brain signaling pathways and the prevalence of neurological conditions with gut-related comorbidities, the scope of this program would be inclusive of a wide range of neurological outcomes, including mental health disorders and chronic neurodegenerative conditions such as Parkinson’s disease and Alzheimer’s disease. The objective of this program is to develop gut-focused intervention strategies (e.g., probiotics, microbial biomarkers, nutritional supplements and novel therapeutics) to decrease risk, slow progression, or possibly reverse these neurological condition(s). Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the R01 activity code. Investigators with expertise and insights into this area of biological mechanisms underlying the effects of environmental exposures on neurological outcomes and the mediating role of the gut-brain axis are encouraged to begin to consider applying for this new NOFO. In addition, collaborative investigations combining expertise in toxicology, microbiome, and neuroscience will be encouraged and these investigators should also begin considering applying for this application. 

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