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Funding Opportunity Announcement for Impact of Environmental Exposures on Gut-Brain Signaling in Neurological Conditions (R01)

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Contract Overview

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The National Institute of Environmental Health Sciences (NIEHS) plans to issue a Notice of Funding Opportunity (NOFO) aimed at supporting research on the gut microbiome-brain axis to enhance detection, prevention, and intervention strategies for neurological diseases caused by environmental exposures. This initiative targets a wide range of neurological outcomes, including mental health disorders and chronic neurodegenerative diseases such as Parkinson’s and Alzheimer’s, with a focus on developing gut-related interventions like probiotics, microbial biomarkers, nutritional supplements, and novel therapeutics to reduce risk, slow disease progression, or potentially reverse these conditions. The funding opportunity will use the R01 activity code and, while applications are not currently being solicited, this notice serves to give prospective applicants ample time to establish collaborations and design responsive projects. Investigators with expertise in the biological mechanisms linking environmental exposures, neurological outcomes, and gut-brain signaling are encouraged to consider applying. Collaborative research combining toxicology, microbiome science, and neuroscience will be highly encouraged to address the complex interactions driving these neurological conditions. Contact information for inquiries is available through the NIEHS, and interested researchers are advised to prepare for the forthcoming solicitation.

General Info

NIEHS plans R01 funding for gut microbiome-brain research on environmental neurological diseases.

Agency

Department Of Health And Human Services → National Institutes Of Health

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology) View NAICS

Place of Performance

Not specified

Set-Aside

NONE

Documents

(0)

No documents available

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Timeline

Posted

forecast

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health
Contacts1 person available
OfficeUS
Organization / Agency
Department Of Health And Human Services → National Institutes Of Health
Office AddressUS
Contacts
Anika L. Dzierlenga Ph.D. National Institute of Environmental Health Sciences (NIEHS
contact@example.gov
+1 (555) 000-0000

Full Description

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The National Institute of Environmental Health Sciences (NIEHS) intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for research that builds on our understanding of the gut microbiome-brain axis for the purpose of identifying improved detection, prevention, and intervention strategies for environmental exposure-induced neurological diseases. Given the overlapping gut-brain signaling pathways and the prevalence of neurological conditions with gut-related comorbidities, the scope of this program would be inclusive of a wide range of neurological outcomes, including mental health disorders and chronic neurodegenerative conditions such as Parkinson’s disease and Alzheimer’s disease. The objective of this program is to develop gut-focused intervention strategies (e.g., probiotics, microbial biomarkers, nutritional supplements and novel therapeutics) to decrease risk, slow progression, or possibly reverse these neurological condition(s). Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the R01 activity code. Investigators with expertise and insights into this area of biological mechanisms underlying the effects of environmental exposures on neurological outcomes and the mediating role of the gut-brain axis are encouraged to begin to consider applying for this new NOFO. In addition, collaborative investigations combining expertise in toxicology, microbiome, and neuroscience will be encouraged and these investigators should also begin considering applying for this application. 

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