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In Silico Aging & Physiological Modeling

Active

Federal

Response Deadline10/07/2026, 06:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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This subcontract under the Advanced Research Projects Agency for Health (ARPA-H) involves the computational modeling of organ aging for prime contractors on COSMOS projects. The primary objective is to develop a Baseline In Silico Aging Model prior to flight and integrate data from both Low Earth Orbit and terrestrial twins to quantify the Tissue Aging Rate in Space (TARIS). The scope of work includes providing biologically informed design parameters for MPS fabrication and delivering comprehensive reports on the Baseline In Silico Aging Model and TARIS quantification. This effort falls under NAICS code 541715 and is managed through the Department of Health and Human Services.

General Info

ARPA-H subcontract for computational organ aging models to quantify tissue aging in space.

Agency

Department Of Health And Human Services → Advanced Research Projects Agency For Health (arpa-H)View Agency

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)View NAICS

Place of Performance

DC

Set-Aside

NONE

Documents

This scope was carved out of ARPA-H-SOL-26-165.

The full solicitation package (8 documents), including the RFP, is on the prime solicitation, not on this scope.

View the prime solicitation

ARPA-H Comprehensive Organ System Modeling in Outer Space (COSMOS) Innovative Solutions Opening

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Timeline

PostedSep 16

subcontract

Response DeadlineOct 7

Submission deadline

Response Deadline

10/07/2026, 06:00:00 PM UTCin 21 days

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → Advanced Research Projects Agency For Health (arpa-H)

ContactsNo contacts available

OfficeN/A

Organization / Agency

Department Of Health And Human Services → Advanced Research Projects Agency For Health (arpa-H)

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Office AddressN/A

ContactsNo contact information available

Full Description

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Performs computational modeling of organ aging for prime contractors on ARPA-H COSMOS projects. Develops a Baseline In Silico Aging Model pre-flight and integrates LEO and Terrestrial Twin Data to quantify the Tissue Aging Rate in Space (TARIS). Provides biologically informed design parameters for MPS fabrication. Delivers Baseline In Silico Aging Model and TARIS quantification reports.

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