Interdisciplinary Research Networks to Advance Biomedical Research on Resilience and Health Optimization
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The National Center for Complementary and Integrative Health and the Office of Dietary Supplements plan to release a Notice of Funding Opportunity for Fiscal Year 2027 aimed at supporting interdisciplinary research networks focused on advancing biomedical research related to resilience. This initiative aligns with NIH priorities and broader health objectives set by the Department of Health and Human Services, targeting the optimization of health and well-being across the American population. Resilience, as defined in this context, involves the capacity to resist, recover, adapt, or grow from various stressors that affect individuals across their lifespan, including environmental, physiological, psychological, and social challenges. Funding through the U24 mechanism will facilitate the growth of a collaborative research community by promoting high-impact scientific activities such as meetings, cross-training programs, research collaborations, and small-scale pilot projects that lay the groundwork for future NIH funding. The networks are expected to foster innovation, rigor, and reproducibility in resilience research and actively engage in dissemination efforts, including publishing research frameworks, protocols, and best practices. Emphasis is placed on interdisciplinary collaboration among researchers and clinicians with expertise spanning cellular to community-level domains of resilience science. The opportunity is authorized under Sections 301 and 405 of the Public Health Service Act and relevant federal regulations, with contact information provided for further inquiries.
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The National Center for Complementary and Integrative Health and the Office of Dietary Supplements intend to publish a Notice of Funding Opportunity (NOFO) for Fiscal Year 2027. This NOFO aims to support interdisciplinary research networks to advance biomedical research on resilience, aligning with the priorities of the National Institutes of Health (NIH), the Make America Healthy Again Commission, and the Department of Health and Human Services to optimize the health and well-being of all Americans.
Resilience is defined by the NIH Resilience Research Working Group as the capacity to resist, recover, adapt, or grow from challenges or stressors. Americans across the lifespan face an alarming number of acute and chronic stressors, such as viral infections, burnout, bullying, financial hardship, environmental toxins, and natural disasters that can contribute to development or worsening of chronic diseases, ultimately impacting population health and well-being. Resilience outcomes (i.e., resistance, recovery, adaptation, or growth) can be measured over time and across interconnected systems encompassing the whole person, including individual (e.g., molecular, physiological, psychological), environmental, and community domains.
Utilizing the U24 funding mechanism, this NOFO will support interdisciplinary research networks to grow the resilience research community and accomplish high-impact scientific activities that foster an innovative, rigorous, and reproducible body of resilience research. Appropriate activities include meetings, conferences, interdisciplinary cross-training (e.g. workshops, visiting scholar programs), research collaborations, and other training opportunities. The networks will also support innovative small-scale pilot projects to generate preliminary data in preparation for future NIH grants. Furthermore, the networks will be expected to engage in dissemination and outreach strategies (e.g., publications of research frameworks, reviews, design protocols, and best practices). This NOFO encourages interdisciplinary collaborations of researchers and clinicians with expertise in several domains of resilience science (e.g., cellular, physiological, psychological, social, and environmental). Grant authorities that allow NCCIH to forecast this opportunity are as follows: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.
