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Interdisciplinary Research to Understand the Complex Biology of Resilience to Alzheimer’s and Related Dementias Disease Risk

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Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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The National Institute on Aging is preparing to release a Notice of Funding Opportunity aimed at advancing research on the molecular mechanisms that underlie resilience to Alzheimer's disease and related dementias. This initiative seeks to integrate epidemiologic, genomic, and mechanistic studies using data-driven and systems-based methods, including artificial intelligence and machine learning, to identify molecular and cellular factors that contribute to resilience across diverse populations. The program emphasizes generating high-dimensional molecular data from both brain and peripheral tissues, with longitudinal data to support dynamic modeling of resilience mechanisms and the identification of molecular predictors. Currently, applications are not being accepted; this notice serves to inform potential applicants early, allowing them time to form collaborations and develop research proposals. The funding opportunity will utilize the U01 cooperative agreement mechanism and targets investigators with relevant expertise in aging and neurodegenerative disease research. Interested individuals may contact Suzana Petanceska, Ph.D., at the National Institute on Aging for more information.

General Info

NIA announces funding opportunity for Alzheimer's resilience research using AI, genomics, and longitudinal data.

Agency

Department Of Health And Human Services → National Institutes Of Health

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology) View NAICS

Place of Performance

Not specified

Set-Aside

NONE

Documents

(0)

No documents available

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Timeline

Posted

forecast

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health
Contacts1 person available
OfficeUS
Organization / Agency
Department Of Health And Human Services → National Institutes Of Health
Office AddressUS
Contacts
Suzana Petanceska Ph.D
contact@example.gov
+1 (555) 000-0000

Full Description

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The National Institute on Aging (NIA) intends to publish a Notice of Funding Opportunity (NOFO) that builds upon its investment in data-driven approaches for the purpose of defining molecular mechanisms of resilience in the presence of various types of Alzheimer's disease (AD) and AD-related dementias (ADRD) risk. The goal of this NOFO is to build a robust program that integrates epidemiologic, genomic, and mechanistic research through the use of data driven, systems-based approaches (including the use of artificial intelligence and/or machine learning methods) to discover the molecular/cellular determinants of resilience to AD/ADRD risk across representative populations. The initiative will support the generation of high-dimensional molecular data from brain and peripheral tissues, including longitudinal data, to enable dynamic modeling of resilience mechanisms and to discover molecular predictors of resilience.

Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO intends to utilize the U01 activity code. Investigators with expertise and insights into this area of aging research are encouraged to begin to consider applying for this new NOFO. 

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