Limited Competition for the Adolescent Brain Cognitive Development -Extended (ABCD-E) Study Renewal - Data Analysis, Informatics and Resource Center, and Coordinating Center (U24 Clinical Trial Not Allowed)
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The National Institute on Drug Abuse (NIDA), along with other NIH Institutes and Centers, plans to issue a limited competition notice to fund the renewal of the Data Analysis, Informatics and Resource Center, and the Coordinating Center for the Adolescent Brain Cognitive Development (ABCD) Study. This extended phase will continue the longitudinal follow-up of nearly 12,000 participants who were initially recruited at ages 9-10 and assessed through ages 19-20, tracking their development into early adulthood. The study aims to explore how factors such as physical activity, lifestyle choices, and emerging technological habits interact with biological changes to influence brain development and a range of social, behavioral, academic, and health outcomes, including substance use and mental health disorders. This renewal leverages advanced tools such as brain imaging and wearable sensors to gain deeper insights into adolescent and young adult health, aligned with priority areas under the "Making America Health Again" initiative. Although no applications are currently being solicited, eligible organizations will eventually be invited to apply under a standard NIH peer-review process, ensuring that only proposals of high scientific merit will be considered for funding. The contract supports the continuation of one of the largest and most comprehensive long-term studies in the United States dedicated to understanding child and adolescent brain development.
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The National Institute on Drug Abuse (NIDA), with other NIH Institutes and Centers (ICs), intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for the Data Analysis, Informatics and Resource Center, and the Coordinating Center for the Adolescent Brain Cognitive Development (ABCD) Study. The ABCD study is the largest long-term study of brain development and child and adolescent health in the United States. This renewal will continue to follow the ABCD cohort into adulthood, when many of the outcomes of interest (e.g., substance use disorders, mental health disorders, chronic diseases, and other health conditions) will manifest. The ABCD Study has been highly successful in recruiting a cohort of almost 12,000 participants beginning at ages 9-10 and assessing them to ages 19-20. This proposed renewal would follow these children for five years through their emerging adulthood. By using cutting-edge technology such as brain scans and wearable sensors, scientists have an unprecedented opportunity to determine how young adult experiences (such as physical activity, healthy lifestyles, new technological habits like videogames or social media, and other Making America Health Again priority areas) interact with each other and with a young adult’s changing biology to affect brain development and social, behavioral, academic, health, and other outcomes. Applications are not being solicited at this time. This is a Forecast for a Limited Competition that will invite application(s) from eligible organization(s) to apply. Please see Eligibility Section for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding.
