Limited Competition for the Adolescent Brain Cognitive Development -Extended (ABCD-E) Study-Research Project Sites (U01 Clinical Trial Not Allowed)
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The National Institute on Drug Abuse (NIDA), alongside other NIH Institutes and Centers, plans to issue a Limited Competition Notice of Funding Opportunity to select research sites for the continued Adolescent Brain Cognitive Development (ABCD) Study. This extension aims to follow the original cohort of nearly 12,000 participants, initially recruited at ages 9-10, as they progress through emerging adulthood, approximately five years beyond the current assessments done up to ages 19-20. The continued study will leverage advanced technologies such as brain imaging and wearable sensors to explore how various young adult experiences, including physical activity, lifestyle choices, and new technological habits, interact with biological changes to influence brain development, mental health, substance use disorders, chronic diseases, and other health outcomes. Prospective applicants should note that this announcement is a forecast for a limited competition and does not currently solicit applications. Eligible organizations will be invited to apply, and submissions will undergo the standard NIH peer-review process, with funding awarded only to those demonstrating strong merit. This effort supports the broader goal of understanding critical developmental trajectories during a pivotal life stage, contributing valuable insights into health and behavioral sciences relevant to the adolescent and young adult populations. The NIH maintains point of contact availability for inquiries, emphasizing the collaborative nature of this high-profile longitudinal research initiative.
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The National Institute on Drug Abuse (NIDA), with other NIH Institutes and Centers (ICs), intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for the research sites for the Adolescent Brain Cognitive Development (ABCD) Study. The ABCD study is the largest long-term study of brain development and child and adolescent health in the United States. This renewal will continue to follow the ABCD cohort into adulthood, when many of the outcomes of interest (e.g., substance use disorders, mental health disorders, chronic diseases, and other health conditions) will manifest. The ABCD Study has been highly successful in recruiting a cohort of almost 12,000 participants beginning at ages 9-10 and assessing them to ages 19-20. This proposed renewal would follow these children for five years through their emerging adulthood. By using cutting-edge technology such as brain scans and wearable sensors, scientists have an unprecedented opportunity to determine how young adult experiences (such as physical activity, healthy lifestyles, new technological habits like videogames or social media, and other Making America Health Again priority areas) interact with each other and with a young adult’s changing biology to affect brain development and social, behavioral, academic, health, and other outcomes. Applications are not being solicited at this time. This is a Forecast for a Limited Competition that will invite application(s) from eligible organization(s) to apply. Please see Eligibility Section for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding.
