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Limited Competition for the Continuation of the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) Administrative Resource (U24 Clinical Trials Optional)

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The National Institutes of Health, through the National Institute on Alcohol Abuse and Alcoholism, is forecasting a limited competition renewal for the National Consortium on Alcohol and Neurodevelopment in Adolescence administrative resource. Utilizing the U24 activity code, this initiative aims to extend the longitudinal study of over 800 individuals to track participants up to 37 years of age. The primary goal is to analyze how the timing of adolescent alcohol consumption impacts brain structure, function, and psychiatric health as individuals transition into emerging adulthood. This research is designed to differentiate between the effects of early and late onset drinking to inform evidence-based prevention strategies and early intervention approaches for alcohol use disorder. By understanding the enduring and transient consequences of adolescent drinking on adult behavior and brain function, the project seeks to improve long-term health outcomes and quality of life. While applications are not currently being solicited, the notice serves to allow investigators with expertise in developmental neuroscience to establish the necessary collaborations for future submission.

General Info

NIAAA renews NCANDA to study adolescent alcohol effects on brain development into adulthood.

Agency

Department Of Health And Human Services → National Institutes Of Health

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

Place of Performance

Not specified

Set-Aside

NONE

Documents

0

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health
Contacts1 person available
OfficeUSA
Organization / AgencyDepartment Of Health And Human Services → National Institutes Of Health
Office AddressUSA
Contacts
Shailesh Kumar National Institute on Alcohol Abuse and Alcoholism (NIAAA
contact@example.gov
+1 (555) 000-0000

Full Description

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The National Institute on Alcohol Abuse and Alcoholism (NIAAA) launched the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) in 2012 to determine how adolescent alcohol-related disruption of normal brain growth patterns of structure, related brain function, and psychiatric health affects brain functioning in emerging adulthood. The consortium uses an accelerated longitudinal design and has acquired data on over 800 individuals between the ages of 12 to 32 years. This wide age range covers the period before onset of drinking, the transition from adolescence to young adulthood, the critical period for binge drinking, and the time of maturing out. This unique dataset provides novel information on the enduring and transient consequences of adolescent drinking on adult brain function and behavior. Current studies on adults drinking do not have this type of data. Renewal of this limited competition NOFO will enable NCANDA to continue to follow these participants up to 37 years of age and acquire data critical to understanding how early versus late onset drinking during adolescence differentially impacts drinking behavior in adulthood. This limited competition renewal will provide valuable information for developing evidence-based alcohol prevention strategies and early intervention approaches to prevent the progression to more severe drinking and AUD thereby preventing the development of chronic disease, improving health outcomes, and increasing quality of life and longevity. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the U24 activity code. Investigators with expertise and insights into this area of developmental neuroscience are encouraged to begin to consider applying for this new NOFO. 

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