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Limited Competition for the Continuation of the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) Administrative Resource (U24 Clinical Trials Optional)

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The National Institute on Alcohol Abuse and Alcoholism (NIAAA) is supporting the renewal of the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA), a longitudinal study begun in 2012 that investigates how adolescent alcohol use affects brain development, function, and psychiatric health into emerging adulthood. NCANDA has collected extensive data from over 800 individuals aged 12 to 32, covering critical periods such as the onset of drinking, adolescence to young adulthood transition, binge drinking phases, and maturing out. This research provides unique insights into the lasting and temporary effects of adolescent alcohol consumption on adult brain function and behavior, surpassing what current adult drinking studies offer. The limited competition renewal will extend follow-up of participants up to age 37, enabling researchers to differentiate the impacts of early versus late adolescent drinking on adult drinking behaviors. This continuation is poised to inform evidence-based prevention strategies and early interventions aimed at reducing severe alcohol use disorder (AUD), thereby preventing chronic disease and improving health outcomes and quality of life. Although applications are not currently being solicited, the announcement gives prospective investigators in developmental neuroscience time to form collaborations and plan responsive projects. The project will use the U24 activity code and is supported by the NIH within the Department of Health and Human Services.

General Info

NIAAA renews NCANDA to study adolescent alcohol effects on brain development into adulthood.

Agency

Department Of Health And Human Services → National Institutes Of Health

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology) View NAICS

Place of Performance

Not specified

Set-Aside

NONE

Documents

(0)

No documents available

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Timeline

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forecast

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health
Contacts1 person available
OfficeUS
Organization / Agency
Department Of Health And Human Services → National Institutes Of Health
Office AddressUS
Contacts
Shailesh Kumar National Institute on Alcohol Abuse and Alcoholism (NIAAA
contact@example.gov
+1 (555) 000-0000

Full Description

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The National Institute on Alcohol Abuse and Alcoholism (NIAAA) launched the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) in 2012 to determine how adolescent alcohol-related disruption of normal brain growth patterns of structure, related brain function, and psychiatric health affects brain functioning in emerging adulthood. The consortium uses an accelerated longitudinal design and has acquired data on over 800 individuals between the ages of 12 to 32 years. This wide age range covers the period before onset of drinking, the transition from adolescence to young adulthood, the critical period for binge drinking, and the time of maturing out. This unique dataset provides novel information on the enduring and transient consequences of adolescent drinking on adult brain function and behavior. Current studies on adults drinking do not have this type of data. Renewal of this limited competition NOFO will enable NCANDA to continue to follow these participants up to 37 years of age and acquire data critical to understanding how early versus late onset drinking during adolescence differentially impacts drinking behavior in adulthood. This limited competition renewal will provide valuable information for developing evidence-based alcohol prevention strategies and early intervention approaches to prevent the progression to more severe drinking and AUD thereby preventing the development of chronic disease, improving health outcomes, and increasing quality of life and longevity. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the U24 activity code. Investigators with expertise and insights into this area of developmental neuroscience are encouraged to begin to consider applying for this new NOFO. 

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