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Limited Competition for the Continuation of the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) Data Analysis Resource (U24 Clinical Trials Optional)

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The National Institute on Alcohol Abuse and Alcoholism (NIAAA) is continuing support for the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA), which studies how adolescent alcohol use affects brain development, function, and psychiatric health into adulthood. Since its inception in 2012, NCANDA has collected data from over 800 participants aged 12 to 32, covering key developmental phases from pre-drinking, through adolescence and young adulthood, to the period of potentially maturing out of risky drinking behaviors. This dataset provides unique insights into the long-term and short-term impacts of adolescent drinking on adult brain function and behavior, information not available from studies focusing solely on adult drinking populations. This renewal, conducted through a limited competition and utilizing the U24 funding mechanism, aims to extend longitudinal follow-up of participants until age 37. The continuation will deepen understanding of how the timing of alcohol use onset during adolescence influences adult drinking patterns, aiding the development of evidence-based prevention and early intervention strategies to reduce progression to severe alcohol use disorder and related chronic diseases. Although applications are not currently being solicited, this notice invites researchers with relevant expertise in integrative neuroscience to prepare for future opportunities to collaborate on this important initiative.

General Info

NIAAA renews NCANDA study to track adolescent alcohol use effects on brain through age 37.

Agency

Department Of Health And Human Services → National Institutes Of Health

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology) View NAICS

Place of Performance

Not specified

Set-Aside

NONE

Documents

(0)

No documents available

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Timeline

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forecast

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health
Contacts1 person available
OfficeUS
Organization / Agency
Department Of Health And Human Services → National Institutes Of Health
Office AddressUS
Contacts
Dominique Lorang-Leins National Institute on Alcohol Abuse and Alcoholism (NIAAA
contact@example.gov
+1 (555) 000-0000

Full Description

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The National Institute on Alcohol Abuse and Alcoholism (NIAAA) launched the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) in 2012 to determine how adolescent alcohol-related disruption of normal brain growth patterns of structure, related brain function, and psychiatric health affects brain functioning in emerging adulthood. The consortium uses an accelerated longitudinal design and has acquired data on over 800 individuals between the ages of 12 to 32 years. This wide age range covers the period before onset of drinking, the transition from adolescence to young adulthood, the critical period for binge drinking, and the time of maturing out. This unique dataset provides novel information on the enduring and transient consequences of adolescent drinking on adult brain function and behavior. Current studies on adults drinking do not have this type of data. Renewal of this limited competition NOFO will enable NCANDA to continue to follow these participants up to 37 years of age and acquire data critical to understanding how early versus late onset drinking during adolescence differentially impacts drinking behavior in adulthood. This limited competition renewal will provide valuable information for developing evidence-based alcohol prevention strategies and early intervention approaches to prevent the progression to more severe drinking and AUD thereby preventing the development of chronic disease, improving health outcomes, and increasing quality of life and longevity. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the U24 activity code. Investigators with expertise and insights into this area of integrative neuroscience are encouraged to begin to consider applying for this new NOFO. 

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