Limited Competition for the HEAL Initiative: HEALthy Brain and Child Development (HBCD) Study (Collaborative U01- Clinical Trial Not Allowed)
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The National Institute on Drug Abuse (NIDA), in collaboration with other NIH Institutes and Centers including the NIH HEAL Initiative, plans to issue a Notice of Funding Opportunity for a limited competition focused on the HEALthy Brain and Child Development (HBCD) study. This study involves a large, longitudinal cohort of approximately 7,200 pregnant women and their children, starting in the second trimester and continuing through childhood. The cohort specifically includes children exposed prenatally or perinatally to substances such as prescription and illicit opioids, marijuana, stimulants, alcohol, and nicotine. The research will involve participant recruitment and retention, behavioral assessments, biospecimen collection, and neuroimaging, aiming to deepen understanding of factors influencing brain development and overall child health, which is crucial for developing effective interventions. This opportunity represents a renewal for the second five-year funding period and will use the U01 activity code. Applications will undergo NIH standard peer review, with funding awarded only to meritorious proposals. Currently, applications are not being solicited; the notice is intended to allow potential applicants sufficient time to prepare collaborations and responsive projects for the upcoming competition. The contact for further information is Dr. Janani Prabhakar, and additional details will be available on Grants.gov when the opportunity is formally announced.
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The National Institute on Drug Abuse (NIDA), with other NIH Institutes and Centers (ICs) , and including the NIH HEAL Initiative, intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for research projects that will be responsible for participant recruitment and retention, behavioral assessments, biospecimen collection, and neuroimaging for the HEALthy Brain and Child Development (HBCD) study. This is a Forecast for a Limited Competition that will invite application(s) from eligible organization(s) to apply. Please see Eligibility Section for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding.
HBCD is a large cohort of pregnant women and their children (~N = 7,200 dyads) beginning in the 2nd trimester of pregnancy and followed longitudinally through childhood. This is a renewal that will continue the funding for the second 5-year period. The cohort includes babies exposed pre- or perinatally to prescription and illicit opioids, marijuana, stimulants, alcohol and/or nicotine, and will provide a deep, nuanced understanding of the short-term and long-term factors that affect a child’s health, brain, and behavioral development, which is an essential first step toward designing interventions that promote well-being and resiliency in children. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This limited competition NOFO will utilize the U01 activity code.