Limited Competition: Post-Stroke Vascular Contributions to Cognitive Impairment and Dementia (VCID) in the United States (U19 - Clinical Trial not Allowed)
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Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.
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The National Institute of Neurological Disorders and Stroke, in collaboration with the National Institute on Aging, plans to issue a Notice of Funding Opportunity targeting research on specific types of stroke events that contribute to cognitive impairment and dementia among post-stroke populations in the United States. With a significant portion of individuals experiencing strokes during their lifetime and a high prevalence of dementia among stroke survivors, this funding opportunity aims to address the critical public health issue of post-stroke cognitive decline. The research sought will focus on identifying clinical factors that may interact synergistically with stroke to cause these cognitive outcomes. While applications are not yet being accepted, this advance notice is intended to provide researchers ample time to build collaborations and prepare proposals. The funding opportunity will use the U19 mechanism and encourages investigators with expertise in stroke, cognitive impairment, dementia, genetics, neuroimaging, biomarkers, biostatistics, and longitudinal studies to consider applying. The initiative emphasizes multidisciplinary investigations designed to advance understanding and address the complex mechanisms linking vascular injury from stroke to cognitive decline, with clinical trials excluded from this opportunity. Interested parties are encouraged to reach out to the designated contact for further information.
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The National Institute of Neurological Disorders and Stroke, with the National Institute on Aging, intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for research on the specific subsets of stroke events that cause cognitive impairment and dementia in post-stroke populations in the United States. With one in three people having a clinical stroke during their lifetime and dementia occurring in an estimated 30% of post-stroke patients, the public health impact of post-stroke cognitive impairment is high. Additional research to understand what clinical factors may causally synergize with stroke to result in cognitive impairment and dementia outcomes is needed.
Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the U19 activity code. Investigators with expertise and insights into this area and awards made under RFA-NS-19-012 are encouraged to begin to consider applying for this new NOFO. In addition, collaborative investigations combining expertise in stroke, cognitive impairment and dementia, genetics, neuroimaging and other biomarkers, biostatistics, and longitudinal observational studies will be encouraged.
