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Mechanistic Exploration of Therapeutic Targets and Treatable Traits to Improve CNS Outcomes in People with HIV

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Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

AI Contract Overview

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The National Institute of Mental Health (NIMH) plans to release a Notice of Funding Opportunity aimed at supporting research focused on identifying modifiable targets and mechanisms to address central nervous system (CNS) complications in individuals living with HIV. This initiative encourages applications that utilize patient-derived data and innovative model platforms to discover and validate new therapeutic targets. Emphasizing advances in systems biology, the research should aim to uncover mechanisms that contribute to CNS dysfunction through clinical or pre-clinical studies. The ultimate goal is to facilitate the development of targeted, mechanism-based interventions tailored to the complex and varied nature of CNS issues in this population. Although applications are not currently being solicited, this announcement is intended to provide prospective applicants ample time to form collaborative partnerships and design responsive projects. The opportunity will be issued under the R01 activity code, and investigators with expertise in systems biology, pre-clinical models, clinical trial methods, and translational neurobiology are particularly encouraged to apply. The point of contact for more information is Vasudev R Rao at the National Institute of Mental Health.

General Info

NIMH seeks research on CNS complications in HIV, targeting therapeutic mechanisms using patient data.

Agency

Department Of Health And Human Services → National Institutes Of Health

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology) View NAICS

Place of Performance

Not specified

Set-Aside

NONE

Documents

(0)

No documents available

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Timeline

Posted

forecast

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health
Contacts1 person available
OfficeUS
Organization / Agency
Department Of Health And Human Services → National Institutes Of Health
Office AddressUS
Contacts
Vasudev R Rao MS. National Institute of Mental Health (NIMH
contact@example.gov
+1 (555) 000-0000

Full Description

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The National Institute of Mental Health intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for research to identify modifiable targets and mechanisms to alleviate clinically relevant central nervous system (CNS) complications in people with HIV. This NOFO supports research that leverages patient derived data and innovative model platforms to identify and validate novel therapeutic targets underlying CNS complications. Building on advances in systems biology, this initiative seeks to identify modifiable mechanisms contributing to CNS dysfunction through clinical studies or pre-clinical model systems. The ultimate goal is to accelerate the development of effective, mechanism-based interventions that address the multifactorial and heterogeneous nature of CNS complications. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the R01 activity code. Investigators with expertise in systems biology, pre-clinical models, clinical trial methodologies and translational neurobiology should consider applying to this NOFO. 

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