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Metastasis Research Network (U54 Clinical Trial Not Allowed)

Active
Grant

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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The National Cancer Institute (NCI) is seeking applications for U54 Specialized Centers to support the Metastasis Research Network (MetNet), aimed at advancing a comprehensive and cohesive understanding of cancer metastasis. Each MetNet Center should propose a unifying scientific theme explored through two or three inter- and multidisciplinary basic research projects that employ integrative, systems-level approaches. These projects are expected to elucidate the complex, non-linear, and dynamic biological processes involved in metastasis, focusing on the interplay between key factors such as early dissemination, microenvironment interactions, dormancy, and metastatic cell responses to therapy. Research on all cancer types, including rare and pediatric metastatic cancers, is encouraged. The goal of this effort is to deepen understanding of metastasis as a whole-body, systems-level problem, promoting new insights into its mechanisms and potential therapeutic strategies. The solicitation does not allow clinical trials, emphasizing basic research that can integrate knowledge across different biological scales and disciplines. The program is managed by the National Institutes of Health, Department of Health and Human Services, with Joanna M. Watson, Ph.D., as the primary contact for applicants. The initiative reflects a strategic push to foster collaborative centers that will serve as hubs for metastasis research through innovative and integrative scientific themes.

General Info

NCI seeks U54 Centers for integrative, multidisciplinary metastasis research excluding clinical trials.

Agency

Department Of Health And Human Services → National Institutes Of Health

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology) View NAICS

Place of Performance

Not specified

Set-Aside

NONE

Documents

(0)

No documents available

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Timeline

Posted

forecast

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health
Contacts1 person available
OfficeUS
Organization / Agency
Department Of Health And Human Services → National Institutes Of Health
Office AddressUS
Contacts
Joanna M. Watson Ph.D
contact@example.gov
+1 (555) 000-0000

Full Description

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Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) solicits applications for research on developing a comprehensive and cohesive understanding of cancer metastasis. Towards this goal, the NCI will support U54 Specialized Centers that together will continue to serve as the hub of the Metastasis Research Network (MetNet). Each MetNet Center should propose an overarching scientific theme that will be pursued through two or three scientific inter- and multidisciplinary basic research projects. The projects should use integrative system level approaches to elucidate and integrate a mechanistic understanding of the non-linear, dynamic, and emergent processes in metastasis. Overarching themes should encompass the interplay between at least two central elements in the metastatic process such as early dissemination, cellular, soluble and/or physical microenvironment crosstalk, dormancy, or mechanisms of responses by metastatic cells to therapies. Studies on all types of cancer are welcome, including rare and pediatric metastatic cancers. 

Research proposed by MetNet Centers is expected to advance our understanding towards a more comprehensive appreciation of metastasis as a whole body, systems-level problem.

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