This Government Contract opportunity from Department Of Health And Human Services was posted on April 24, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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Pharmacological Receptor Interaction Studies

Closed

Federal

Submission Closed05/04/2026, 06:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 541612

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AI Contract Overview

The contract seeks to investigate the role of the 5-HT5A receptor through pharmacological intervention using SB-699551, a selective antagonist, to assess its functional impact on cellular signaling and gene expression. Key experimental readouts include real-time measurements of intracellular calcium dynamics and comprehensive transcriptomic profiling to identify downstream molecular changes induced by receptor modulation. The study aims to clarify the physiological and pathological implications of 5-HT5A receptor activity by correlating pharmacological blockade with measurable cellular responses. This subcontract is issued under the NAICS code 541612, indicating it falls within the category of research and development in the physical, engineering, and life sciences. The solicitation is managed by the FDA Office of Acquisition and Grant Services under the U.S. Department of Health and Human Services, with a deadline for responses set for May 4, 2026. The work is expected to be conducted in a research-oriented environment, though the specific location of performance is not designated, and no set-aside provisions are specified. Interested parties must submit proposals by the stated deadline to be considered for this opportunity.