Precision and Systems Biology to Uncover the Link Between Chronic and Infectious Diseases
Contract Overview
Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.
AI Contract Overview
The National Institute of Allergy and Infectious Diseases is seeking to support multidisciplinary research consortia focused on understanding the complex relationships between chronic illnesses, infectious diseases, and the human microbiome through precision and systems biology approaches. The initiative aims to uncover the biological pathways through which acute infections may trigger long-term health conditions or how pre-existing chronic diseases influence susceptibility and severity of infections. To achieve this, the research will leverage cutting-edge technologies including multi-omics, artificial intelligence, computational modeling, organoid systems, and real-world data integration, alongside longitudinal patient cohorts and comprehensive biobank resources. Enhanced access to digital health records and advanced clinical informatics tools will further enable detailed analysis of genetic, environmental, and lifestyle factors driving disease progression and host-pathogen interactions. The ultimate goal is to generate translational insights that inform new strategies for prevention, diagnosis, and treatment of both chronic and infectious diseases. This opportunity is authorized under Sections 301 and 405 of the Public Health Service Act as amended, and governed by Federal Regulations 42 CFR Part 52 and 2 CFR Part 200. The announcement, posted on June 24, 2026, is a forecast with no solicitation number yet assigned and is open to entities capable of forming collaborative research teams. Questions and communications should be directed to the designated point of contact at NIAID OGAT through the provided email address, and additional information can be found via the official grants.gov link.
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The National Institute of Allergy and Infectious Diseases (NIAID) seeks to advance its mission by supporting multidisciplinary, consortium-based research using precision systems biology approaches to uncover links among chronic illnesses, infectious diseases and microbiomes. There is an urgent scientific and clinical need to understand the pathways by which infections lead to chronic lifelong health issues or alternatively, how long-term illnesses might predispose or exacerbate acute infections. The objective is to harness cutting-edge technologies along with longitudinal patient cohorts and biobank data for comprehensive analysis of genetic, environmental, and lifestyle factors leading to advances in prevention and treatment strategies for both chronic and infectious diseases. The cutting-edge technologies may include multi-omics, computational modeling, artificial intelligence, organoid-based validation systems, and integration of real-world data, alongside improved access to digital health records and advanced clinical informatics tools. The goal is to generate meaningful insights into disease progression and host-pathogen interactions. Grant authorities that allow NIAID to forecast this opportunity are as follows: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.
