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Collaborative Network for Clinical Research on Immune Tolerance

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The National Institute of Allergy and Infectious Diseases, under the Department of Health and Human Services, is forecasting a program to support the Collaborative Network for Clinical Research on Immune Tolerance. This initiative aims to improve the understanding of immune tolerance mechanisms and develop advanced tolerogenic interventions to treat and prevent immune system mediated conditions, including autoimmune diseases, asthma, allergic diseases, and transplant rejection in the liver, kidney, and pancreatic islets. The program focuses on three primary scientific objectives: conducting clinical trials to assess the safety and efficacy of tolerogenic strategies, investigating the basic mechanisms of immune tolerance within those trials, and validating immune assays to monitor tolerance levels. This opportunity is categorized under NAICS code 541715 and is managed by the Division of Allergy, Immunology and Transplantation.

General Info

NIAID funds a clinical network to study and induce immune tolerance in transplant and autoimmune diseases through trials and biomarker validation.

Agency

Department Of Health And Human Services → National Institutes Of Health

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

Place of Performance

Not specified

Set-Aside

NONE

Documents

0

No documents available

Documents will appear here when they are available.

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Timeline

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forecast

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health
Contacts1 person available
OfficeUSA
Organization / AgencyDepartment Of Health And Human Services → National Institutes Of Health
Office AddressUSA
Contacts
Division of Allergy Immunology and Transplantation
contact@example.gov

Full Description

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The National Institute of Allergy and Infectious Diseases (NIAID) seeks to advance its mission through the continued support of the Collaborative Network for Clinical Research on Immune Tolerance. The purpose of this program is to enhance understanding of the underlying mechanisms of the induction, maintenance, and loss of immune tolerance in humans; and to develop improved tolerogenic interventions for the prevention and treatment of immune system mediated diseases (including transplant rejection, autoimmune diseases, and asthma and allergic diseases). The three major scientific goals include: 1) conduct clinical trials to determine the safety and efficacy of promising tolerogenic strategies in liver, kidney and pancreatic islet transplantation; allergic diseases and asthma; and autoimmune diseases; 2) investigate the basic mechanisms of immune tolerance in these diseases as an integral part of clinical trials; and 3) develop, refine and validate immune assays to monitor the induction, maintenance, and loss of tolerance in these disorders. Grant authorities that allow NIAID to forecast this opportunity are as follows: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.

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