Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools
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The National Institutes of Health, under the Department of Health and Human Services, is issuing Notice of Funding Opportunity PAR-27-078 for the Research Enhancement Award Program for Health Professional Schools and Graduate Schools. This initiative is a collaborative effort involving numerous institutes, including the National Institute on Aging, the National Cancer Institute, and the National Institute of Mental Health, among others. The program utilizes the R15 activity code to support small scale research grants at institutions that do not typically receive substantial NIH funding. The primary objective is to enhance the research environment at these institutions and provide critical biomedical research experiences for undergraduate and graduate students, as well as health professional students. The program invites investigator initiated applications for mechanistic studies and minimal risk clinical trials that align with the missions of the participating NIH institutes. Minimal risk clinical trials are specifically defined as those that do not require FDA oversight, do not aim to formally establish efficacy, and pose low risks of physical or psychological harm. This solicitation was posted on June 16, 2025, with application due dates starting July 10, 2026, and an expiration date of October 26, 2027. Interested applicants can submit their proposals through NIH ASSIST, S2S, or the Grants.gov Workspace.
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The National Institute on Aging (NIA), with the National Eye Institute (NEI); National Heart, Lung, and Blood Institute (NHLBI); National Human Genome Research Institute (NHGRI); National Institute on Alcohol Abuse and Alcoholism (NIAAA); Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); National Institute on Deafness and Other Communication Disorders (NIDCD); National Institute on Drug Abuse (NIDA); National Institute of Mental Health (NIMH); National Institute of Nursing Research (NINR); National Institute on Minority Health and Health Disparities (NIMHD); and National Cancer Institute (NCI), intend to publish a Notice of Funding Opportunity (NOFO) as part of the Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools. The participating institutions invite applications that support investigator-initiated mechanistic and/or minimal risk clinical trials addressing the mission and research interests of the participating NIH institutes. For the purposes of this NOFO, minimal risk clinical trials are defined as those that do not require FDA oversight, do not intend to formally establish efficacy, and have low risks to potentially cause physical or psychological harm. The purpose of the REAP for Health Professional Schools and Graduate Schools is to support small scale research grants at institutions that do not receive substantial funding from the NIH, with an emphasis on providing biomedical research experiences primarily for health professional, undergraduate and graduate students and enhancing the research environment at applicant institutions.
Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO intends to utilize the R15 activity code. Investigators with expertise and insights into this area of aging research are encouraged to begin to consider applying for this new NOFO.
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