Research Program Award (R35 Clinical Trial Optional)
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The National Institute of Neurological Disorders and Stroke (NINDS) is preparing to issue a Notice of Funding Opportunity (NOFO) for the Research Program Award (RPA) under the R35 activity code. This initiative aims to provide eligible Program Directors and Principal Investigators with longer-term financial support and greater flexibility, allowing them to focus more on conducting research and mentoring rather than managing multiple grant applications. The funding supports a broad range of career stages and encourages investigators to pursue innovative and long-term research projects that align closely with NINDS's mission. Applications are not currently being accepted; the advance notice is intended to give researchers ample time to develop collaborative and responsive proposals. The RPA offers several key benefits, including a more stable funding environment conducive to ambitious, extended research endeavors and the freedom to explore new opportunities as they arise without being confined to specific aims. This flexibility reduces the administrative burden on investigators, enabling them to dedicate more time to laboratory work and the mentorship of students and postdoctoral fellows. However, research proposals must be relevant to the mission of NINDS, as projects outside this scope or traditionally supported by other NIH Institutes or Centers will not be considered. The program is designed to strengthen the biomedical workforce by supporting investigators in their scientific and mentoring efforts.
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Full Description
The National Institute of Neurological Disorders and Stroke (NINDS) intends to publish a Notice of Funding Opportunity (NOFO) to provide longer-term support, and increased freedom and flexibility, to Program Directors (PDs)/Principal Investigators (PIs), to allow them to redirect their time away from the administrative burden of writing and managing multiple grant applications and towards engaging in the lab. This Research Program Award (RPA) affords investigators at most career stages the opportunity to advance their long-term research goals, rigorously explore exciting research opportunities, and mentor students and postdoctorates, which support and align with the mission of NINDS. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the R35 activity code. This funding stability will provide eligible investigators increased security, allowing them to undertake research projects that require a longer timeframe or to embark upon research that breaks new ground. Research activities outside the NINDS mission, or traditionally supported by another NIH Institute or Center, will not be considered through this program.
Benefits of the RPA include:
- A more stable funding environment, facilitating the pursuit of longer-term research goals;
- Flexible funding, enabling investigators to pursue research opportunities as they arise, not tied to specific aims;
- Reduced time spent writing grant applications and managing multiple grant awards, allowing investigators to spend more time conducting and overseeing research;
- More time for PDs/PIs to mentor the biomedical workforce.
