Resource and Capacity Building to Advance the Science of Aggression across Species and Disciplines (R24 Clinical Trial Optional)
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Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.
AI Contract Overview
The National Institutes of Health, through the Office of Behavioral and Social Sciences Research, is preparing to release a funding opportunity focused on advancing research into the mechanisms of aggressive behavior across species and disciplines. This initiative aims to address the association of aggressive behavior with various chronic diseases, particularly psychiatric and neurological disorders, by improving mechanistic understanding, prevention, and treatment. Key emphasis is placed on developing naturalistic and ecologically valid experimental paradigms that apply across both animal and human studies to bridge disciplinary gaps. The program also prioritizes the creation of improved measurement tools to enhance causal inference, rigor, and reproducibility, as well as the establishment of cross-species data repositories integrating behavioral, brain, genetic, and physiological data to propel research and improve health outcomes. The funding opportunity will employ the R24 activity code and is currently in a forecast phase, allowing interested researchers time to form collaborative and multidisciplinary teams. Target applicants include experts from neuroscience, psychology, evolutionary biology, behavioral genetics, sociology, criminology, ethics, and related fields, encouraging partnerships that combine animal and human research approaches. The initiative supports team science, mentorship, career development, integrated bioethical perspectives, and outreach efforts to ensure that the research remains relevant and practically applicable. While applications are not being accepted at this time, prospective applicants are encouraged to begin developing meaningful collaborations in anticipation of the forthcoming solicitation.
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The Office of Behavioral and Social Sciences Research seeks to advance its mission by soliciting applications to advance research on the mechanisms of aggressive behavior across species and disciplines, consistent with OBSSR’s Congressional authorization to develop and coordinate research on violent behavior. Aggressive behavior is associated with numerous chronic diseases, especially psychiatric and neurological conditions. Additional scientific resources and capacity are needed to accelerate and enhance research to address this public health challenge through improved mechanistic understanding, prevention, and treatment of aggressive behavior. Priority areas for this NOFO will include: naturalistic and ecologically valid experimental paradigms that can be applied analogously across both animal and human research to bridge disciplinary silos and translational gaps; improved measurement tools to catalyze progress and improve causal inference, rigor, and reproducibility; and cross-species data repositories (e.g., behavioral, brain, genetic, and physiological data) to accelerate research advances to improve human health and well-being. Priority approaches will include: team science to promote innovation and collaboration across levels of analysis, disciplines, and the translational continuum; mentorship and career development to build a robust cohort of investigators; integrated bioethical perspectives; and outreach to and collaboration among researchers, practitioners, and patients to ensure use-inspired research with a strong foundational basis.
Applications are not being solicited at this time. This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the R24 activity code.
Investigators with expertise in neuroscience, psychology, evolutionary biology, behavioral genetics, sociology, criminology, ethics, and other related disciplines are encouraged to begin to consider applying for this new NOFO. Collaborative teams combining expertise in animal and human research will be encouraged.