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Resource and Capacity Building to Advance the Science of Aggression across Species and Disciplines (R24 Clinical Trial Optional)

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The National Institutes of Health, through the Office of Behavioral and Social Sciences Research, is issuing a forecast for a grant opportunity under the R24 activity code focused on advancing the science of aggression across species and disciplines. The initiative aims to improve the mechanistic understanding, prevention, and treatment of aggressive behavior, which is linked to various psychiatric and neurological conditions. Key priorities include the development of ecologically valid experimental paradigms, improved measurement tools for better causal inference, and the creation of cross-species data repositories encompassing behavioral, genetic, and physiological data. The program emphasizes a multidisciplinary approach, encouraging team science and collaborations between animal and human research. It seeks investigators with expertise in fields such as neuroscience, psychology, evolutionary biology, sociology, and ethics to bridge translational gaps. While applications are not currently being accepted, this notice serves to allow potential applicants time to establish collaborations and develop projects. The initiative also prioritizes mentorship, career development, and the integration of bioethical perspectives and patient outreach to ensure research is both foundational and use-inspired.

General Info

NIH to fund multidisciplinary research on aggressive behavior mechanisms integrating cross-species studies.

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health
Contacts1 person available
OfficeUSA
Office AddressUSA
Contacts
Kristin Brethel-Haurwitz Office of Behavioral and Social Sciences Research

Full Description

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The Office of Behavioral and Social Sciences Research seeks to advance its mission by soliciting applications to advance research on the mechanisms of aggressive behavior across species and disciplines, consistent with OBSSR’s Congressional authorization to develop and coordinate research on violent behavior. Aggressive behavior is associated with numerous chronic diseases, especially psychiatric and neurological conditions. Additional scientific resources and capacity are needed to accelerate and enhance research to address this public health challenge through improved mechanistic understanding, prevention, and treatment of aggressive behavior. Priority areas for this NOFO will include: naturalistic and ecologically valid experimental paradigms that can be applied analogously across both animal and human research to bridge disciplinary silos and translational gaps; improved measurement tools to catalyze progress and improve causal inference, rigor, and reproducibility; and cross-species data repositories (e.g., behavioral, brain, genetic, and physiological data) to accelerate research advances to improve human health and well-being. Priority approaches will include: team science to promote innovation and collaboration across levels of analysis, disciplines, and the translational continuum; mentorship and career development to build a robust cohort of investigators; integrated bioethical perspectives; and outreach to and collaboration among researchers, practitioners, and patients to ensure use-inspired research with a strong foundational basis. 


Applications are not being solicited at this time. This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the R24 activity code.  


Investigators with expertise in neuroscience, psychology, evolutionary biology, behavioral genetics, sociology, criminology, ethics, and other related disciplines are encouraged to begin to consider applying for this new NOFO. Collaborative teams combining expertise in animal and human research will be encouraged. 

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