Single source: Childhood Cancer Survivor Study (U24 Clinical Trial Not Allowed)
Contract Overview
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AI Contract Overview
The National Cancer Institute (NCI) is issuing a Notice of Funding Opportunity to continue supporting the Childhood Cancer Survivor Study (CCSS), which focuses on understanding the long-term health outcomes of individuals who survived pediatric and adolescent cancers. This extensive collaborative study currently includes health data from over 38,000 survivors who have lived at least five years post-treatment, along with a sibling comparison group. The initiative aims to expand by gathering new longitudinal data, particularly focusing on aging survivors and those treated with contemporary therapies. The CCSS serves as both a comprehensive data repository and biorepository, enabling researchers to conduct risk assessments and study the impact of cancer treatments on survivors' health over their lifespan. This funding opportunity is limited to a single-source application process and encourages eligible organizations to apply under strict NIH peer-review standards, ensuring that only highly meritorious proposals receive funding. The primary objective is to further cancer research by facilitating observational and interventional studies that could lead to improved treatment approaches and better long-term health outcomes for childhood cancer survivors. Potential applicants are advised to consult the eligibility criteria and contact the designated NCI representative for further information.
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Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) intends to support the continuation of the Childhood Cancer Survivor Study (CCSS) that investigates the long-term morbidity and mortality associated with cancer treatments. The CCSS represents a multi-institutional, multidisciplinary collaborative research resource that currently has health-related data from 38,000 or more 5-year survivors of pediatric and adolescent cancer patients with a comparison sibling control cohort. This NOFO seeks to obtain additional age-related longitudinal information from the current cohort of survivors and to include pediatric cancer survivors receiving modern therapies. The goal of the CCSS is to serve as a data resource and a biorepository for researchers. The objectives are to use the resources to conduct cancer risk assessments, observational and intervention-based research studies associated with long-term outcomes across the life span of survivors with the intent of improving cancer treatments. This is a Forecast for a single source that will invite application(s) from eligible organization(s) to apply. Please see the Eligibility Section for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding.
