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The NIDDK Inflammatory Bowel Disease Genetics Consortium (IBDGC) Data Coordinating Center

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Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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The National Institute of Diabetes and Digestive Diseases and Nutrition (NIDDK) is continuing its Inflammatory Bowel Disease Genetics Consortium (IBDGC) to further investigate the genetic underpinnings of inflammatory bowel disease (IBD). The consortium has already identified over 300 genetic risk loci associated with various IBD subtypes and elucidated some biological mechanisms involved. Despite progress in understanding and treating IBD, it remains a chronic and complex disease lacking diagnostic biomarkers and reliable predictors for outcomes such as remission, recurrence, and treatment response. The IBDGC aims to address these gaps by integrating patient cohorts, biospecimens, and data science tools to explore the interplay between genetic, clinical, and environmental factors in IBD development and progression, ultimately enhancing precision medicine approaches. The Data Coordinating Center (DCC) of the IBDGC will play a central role in managing collaboration among genetic research centers, external scientific partners, and pilot projects. Responsibilities of the DCC include overseeing participant enrollment, coordinating biospecimen collection and processing, and managing data and sample submissions to centralized repositories. This coordination is vital to streamlining research activities and ensuring the consistency and quality of data necessary to develop improved predictive tools and therapeutic strategies for IBD patients. The contract is managed under the Department of Health and Human Services with a designated point of contact available for further inquiries.

General Info

NIDDK funds IBDGC to study genetics, coordinate data, improve IBD diagnosis and treatment.

Agency

Department Of Health And Human Services → National Institutes Of Health

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology) View NAICS

Place of Performance

Not specified

Set-Aside

NONE

Documents

(0)

No documents available

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Timeline

Posted

forecast

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health
Contacts1 person available
OfficeUS
Organization / Agency
Department Of Health And Human Services → National Institutes Of Health
Office AddressUS
Contacts
Ludmila Pawlikowska Ph.D
contact@example.gov
+1 (555) 000-0000

Full Description

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The National Institute of Diabetes and Digestive Diseases and Nutrition (NIDDK) seeks to advance its mission by continuing the NIDDK Inflammatory Bowel Disease Genetics Consortium (IBDGC). The IBDGC has led collaborative efforts resulting in the identification of >300 genetic risk loci for different IBD subtypes across patient populations and characterization of underlying biological mechanisms. Despite advances in biological understanding and the development of a range of biologic therapies, IBD remains a chronic, severe and heterogenous disease with no cure requiring multiple interventions over the life course. Diagnostic biomarkers and accurate predictors of critical outcomes including disease remission, recurrence, and response to specific therapies are lacking. The IBDGC will leverage patient cohorts, biospecimens and advances in data science to characterize the interactions of genetic, clinical and environmental factors in disease development and progression, and to develop new predictors of disease outcomes, with the goal of improving medical management and advancing precision medicine for IBD patients. The Data Coordinating Center (DCC) of the IBDGC will coordinate collaboration among IBDGC Genetic Research Centers (described in the companion notice), external scientific collaborations and pilot projects, participant enrollment, biospecimen collections and processing, and manage the submission of data and samples to central databases and repositories. 

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