Using Archived Data and Specimen Collections to Advance Maternal and Pediatric HIV/AIDS Research
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The National Institutes of Health, specifically the Eunice Kennedy Shriver National Institute of Child Health and Human Development and the National Institute of Mental Health, is soliciting R21 exploratory and developmental research grant applications under solicitation RFA-HD-27-007. This initiative focuses on the secondary use of archived HIV-related data and biospecimen collections to advance research concerning maternal, pediatric, and adolescent HIV. The program encourages the integration of interdisciplinary perspectives and innovative data science methods to generate new insights from existing datasets and address persistent research questions in maternal and child health. This solicitation, which is a reissue of RFA-HD-25-009, was posted on July 8, 2025, with an expiration date of October 21, 2028. Applications are accepted through 2028, and the opportunity is categorized under NAICS code 541715. The project is managed by the Maternal and Pediatric Infectious Disease Branch and is supported by various public health authorities, including the Public Health Service Act and the Small Business Research and Development Enhancement Act of 1992.
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The Maternal and Pediatric Infectious Disease Branch (MPIDB) of the Eunice Kennedy Shriver National Institute of Child Health and Human Development has a longstanding commitment to the collection and preservation of high-quality HIV-related data and specimens. This Request for Applications will support the secondary use of archived data and/or biospecimen collections, which represents a critical opportunity to advance research in maternal, pediatric, and adolescent HIV. The strategic reuse of these HIV-related datasets and biospecimens is essential to addressing persistent and emerging research questions in maternal and child health. The integration of innovative data science methods, existing research infrastructure, and interdisciplinary perspectives to generate new insights from existing datasets will be strongly encouraged. Grant authorities that allow the Eunice Kennedy Shriver National Institute of Child Health and Human Development to forecast this opportunity are as follows: Public Health Service Act, Section 301, 448 and 487, as amended, Public Laws 78-410 and 99-158, as amended, 42 U.S.C. 241; 42 U.S.C. 285g; 42 U.S.C. 288; Small Business Research and Development Enhancement Act of 1992, Public Law 102-564, Public Law 118-47.
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