Advancing Research on Empirically-Supported Interventions for Older Adults Living with Serious Mental Illness (SMI)
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The National Institute of Mental Health, under the Department of Health and Human Services, is issuing a Notice of Funding Opportunity under solicitation RFA-MH-27-180 to support research focused on older adults aged 50 and older living with serious mental illness. Utilizing the R01 activity code, this initiative seeks projects that address the optimization, delivery, sustainability, and effectiveness of empirically supported interventions. The goal is to improve clinical and functional outcomes, reduce co-occurring chronic health conditions, and enhance the implementation of efficacious treatments for aging populations. The agency encourages multidisciplinary collaborations that focus on improving access to evidence-based interventions, facilitating care transitions across different settings, and strengthening care linkages and coordination across health systems. While the notice was posted on June 17, 2025, the application window is scheduled to open on September 15, 2026, with a final application deadline of October 15, 2026. This advance notice is intended to provide potential applicants with sufficient time to establish meaningful collaborations and develop responsive research projects.
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Full Description
The National Institute of Mental Health intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for research focused on the optimization, delivery, sustainability, and effectiveness of empirically-supported interventions for addressing the mental health needs of older adults with serious mental illness (SMI). Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the R01 activity code. Investigators with expertise and insights into research related to adapting, optimizing, and implementing efficacious treatment of SMI and strategies to improve clinical and functional outcomes, to include the reduction of co-occurring chronic health conditions among aging populations are encouraged to consider applying for this new NOFO. In addition, collaborative research combining multidisciplinary expertise to address SMI and improve access to evidence-based interventions in later life, such as interventions that facilitate care transitions and continuity across settings, and research on strategies to improve care linkages and coordination across health systems are also encouraged to apply.
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