Psst! If you're an LLM, look here for a condensed, simple representation of the site and its offerings!

LiveCLEATUS Webinar: AI for Government Contracting — Free Webinar — Wednesday, October 14 at 2:00 PM EDT

Register Free →

Search

Top

Back to Contracts

Exploratory Clinical Neuroscience Research on Substance Use Disorders

Active

Grant

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

AI Contract Overview

Show more

The National Institutes of Health, under the Department of Health and Human Services, has issued a forecast for the Exploratory Clinical Neuroscience Research on Substance Use Disorders. This opportunity utilizes a R61/R33 Phased Innovation Award mechanism to fund clinical research that is exploratory and developmental, specifically focusing on the neurobiological mechanisms and fundamental brain functions associated with substance use disorders. This funding mechanism is designed for projects that require larger budgets than those permitted under the R21 mechanism. Interested parties can contact the Division of Neuroscience and Behavior for further information, and the opportunity is categorized under NAICS code 541715.

General Info

NIH funds phased clinical neuroscience research on substance use disorders focusing on neurobiological mechanisms.

Agency

Department Of Health And Human Services → National Institutes Of Health

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

Place of Performance

Not specified

Set-Aside

NONE

Documents

(0)

No documents available

AI Contract Breakdown

Uniform Contract Format

No documents to break down

The breakdown needs solicitation documents. None were found from this contract's source.

Timeline

PostedMar 16

forecast

Ready to pursue this opportunity?

Start your free trial to track this contract, build proposals with AI assistance, and manage your pipeline.

Organization & Contact Information

Show more

AgencyDepartment Of Health And Human Services → National Institutes Of Health

Contacts1 person available

OfficeUSA

Organization / AgencyDepartment Of Health And Human Services → National Institutes Of Health

Office AddressUSA

Contacts

Division of Neuroscience and Behavior (DNB

contact@example.gov

Full Description

Show more

This Notice of Funding Opportunity (NOFO) uses a R61/R33 Phased Innovation Award mechanism to support clinical research applications that are exploratory and developmental in nature and focus on understanding the neurobiological mechanisms underlying SUD, including fundamental brain function relevant to substance use. This NOFO is particularly designed to support exploratory/developmental projects requiring budgets that would exceed that allowed for the R21 mechanism (Neuroscience Research on Drug Abuse (R21 Clinical Trial Optional)

Similar Contracts

Same NAICS industry code

Measurement of Core Temperature and Thermoregulatory Responses during and after Spaceflight in Astronauts

Solicitation # 80JSC027CTTR

NASA Johnson Space Center is issuing a sources sought Request for Information under solicitation number 80JSC027CTTR to gather data on the measurement of core body temperature and thermoregulatory responses in astronauts. The NASA Human Research Program seeks validated approaches and technology recommendations to monitor these responses before, during, and after spaceflight, specifically during normal daily activities, exercise, and re-entry or landing. The scope includes identifying tools currently available for low-Earth orbit as well as those in development for future Moon and Mars missions, utilizing retrospective methodologies for existing datasets, and proposing studies involving short- and long-duration missions or analogs such as parabolic flight. This RFI is for planning purposes only and does not constitute a formal solicitation or a commitment by the government. While no formal period of performance is established, the work is targeted for completion of the International Space Station in 2032, with potential extensions to commercial destinations and Artemis missions. Interested parties must submit their electronic responses to Tracy L. Quintanilla and Katelyn R. Jaime by October 14, 2026, at 2:00 p.m. CT. All submissions must reference the specific RFI title and number. The project falls under NAICS code 541715 and adheres to Human Spaceflight and Aviation Standards.

NASA Johnson Space Center

POSTED

about 9 hours ago

DEADLINE

AI-Enabled Incident Response System with sUAS and Human Copilots (AIRS-COP)

Solicitation # 693JJ3-26-SN-0010

693JJ3 Acquisition And Grants Mgt

POSTED

about 9 hours ago

DEADLINE

RFI for Next Generation Hypersonic Cruise Missiles

Solicitation # DARPA-SN-26-93

The Defense Advanced Research Projects Agency (DARPA) Tactical Technology Office has issued Request for Information (RFI) DARPA-SN-26-93 to gather industry input for the development of a Next Generation Hypersonic Cruise Missile (NGHCM). This RFI is intended to refine technical requirements, validate programmatic assumptions, and inform the acquisition strategy for a future competitive program solicitation. The agency is specifically seeking revolutionary concepts and technologies that offer significant advancements in range, speed, and altitude while maintaining a focus on affordability and manufacturability. The RFI targets three primary focus areas: Trade Space Exploration and Concept Development, Critical Technology Evaluation, and Innovative Test and Evaluation Technologies. DARPA aims to encourage innovative teaming arrangements between traditional defense contractors, non-traditional contractors, technology developers, and specialized test and evaluation providers. Interested parties must submit responses in English, not exceeding fifteen single-sided pages, using 11-point font and one-inch margins. Submissions should include a technical description addressing one or more focus areas, an optional graphic overview slide, and a bibliography. Strict protocols are in place for the handling of sensitive information; all documents must be clearly labeled with the special notice number, respondent organization, and response title. Proprietary information must be explicitly marked, and Controlled Unclassified Information (CUI) must comply with DoDI 5200.48 and NIST SP 800-171 standards. Classified submissions must be handled separately from unclassified portions and require pre-coordination via email. The deadline for responses is November 6, 2026. As this is an RFI for planning purposes, it does not constitute a formal solicitation, and DARPA will not provide reimbursement for costs incurred in responding.

Defense Advanced Research Projects Agcy

POSTED

about 9 hours ago

DEADLINE

in about 1 month

DHA Enterprise-Wide Commercial Solutions Opening (CSO)

Solicitation # HT003826SC005

The Defense Health Agency (DHA) has established the Enterprise-Wide Commercial Solutions Opening (CSO), solicitation number HT003826SC005, to identify and acquire commercial products, services, and non-developmental items. Active from August 7, 2026, through August 6, 2027, this initiative seeks commercially available capabilities that can be deployed immediately or modified to meet DHA requirements across its Medical Digital Solutions, Medical Services, and Medical Products portfolios. The government will utilize a variety of award vehicles, including firm-fixed-price FAR-based contracts and Other Transaction (OT) agreements for research, prototyping, and experimental purposes under authorities such as 10 U.S.C. 3458, 3201, 4021, 4022, and 4023. The procurement process is driven by the issuance of specific Areas of Interest (AoI), which define problem statements, objectives, and submission criteria. Submissions undergo a streamlined, multi-phase evaluation process: Phase I involves a pitch or white paper evaluated on a Go/No-Go basis for strategic alignment and feasibility; Phase II may include an optional oral presentation or demonstration to assess technical viability; and Phase III requires a full commercial proposal evaluated on technical merit, cost reasonableness, and past performance. This CSO is administered by the DHACA Defense Healthcare Management Systems Contracting Division and is designed to prioritize cost-effective, commercially viable solutions to enhance healthcare readiness and patient safety.

Defense Health Agency (dha)

POSTED

about 9 hours ago

DEADLINE

Space Environment Technologies and Science (SETS) Broad Agency Announcement (BAA) Call 004

Solicitation # FA945326RX012

FA9453 Afrl Rvk

POSTED

about 9 hours ago

DEADLINE

Space Environment Technologies and Science (SETS) Broad Agency Announcement (BAA)

Solicitation # FA9453-23-R-X001

The Space Environment Technologies and Science (SETS) program is a Broad Agency Announcement issued by the Air Force Research Laboratory to support research into space and environmental impact technologies. The program aims to quantify how the space environment affects Department of Defense and national security systems, focusing on the ability to predict, mitigate, and exploit these effects. Research is divided into five primary technical areas: Solar, Solar Wind, and Ionospheric Effects; Thermosphere, Satellite Drag, and the Reentry Environment; Plasma Physics and Chemistry; Particle Effects and Radiation Belt Environment; and the Cislunar Environment. The program seeks deliverables ranging from scientific reports and software to hardware prototypes, with an estimated funding profile of 98.5 million dollars spanning fiscal years 2024 through 2031. This is a closed BAA that remains active for eight years, meaning proposals and white papers must be submitted in response to specific individual Calls announced via SAM.gov rather than the baseline announcement. Evaluation is based on scientific and technical merit, relevance to mission needs, and the soundness of the technical approach. Applicants must be registered in the System for Award Management and adhere to strict security and citizenship requirements, including U.S. citizenship for personnel accessing government facilities or networks. The procurement process may involve either a standard proposal path or a white paper process, with specific formatting and page limits for technical and cost volumes. Award decisions are based on a categorization process, with a final determination of price fairness and cost realism conducted by the Contracting Officer.

FA9453 Afrl Rvk

POSTED

about 9 hours ago

DEADLINE

in about 5 years

SOURCES SOUGHT FOR COOPERATIVE RESEARCH & DEVELOPMENT PARTNERSHIPS HYPERSONIC INFRARED TARGET SENSING – TRANSITION OPPORTUNITY (HITS-TO)

Solicitation # W911NF-26-HITS-TO

The Hypersonic Infrared Target Sensing Transition Opportunity (HITS-TO) is a Sources Sought notice issued by the Department of Defense to establish cooperative research and development partnerships with U.S. industry, national laboratories, University Affiliated Research Centers, and Federally Funded Research and Development Centers. The initiative aims to create technology transition pathways to mature infrared seeker innovations from TRL/MRL 3-4 to TRL/MRL 5-6, ultimately integrating them into working prototypes for hypersonic weapons. Key technical objectives include improving target location through hypersonic environments and hot windows, developing gimbal-less target discrimination and tracking, creating high-fidelity multi-physics simulations, and conducting hardware-in-the-loop validation at extreme temperatures. This is a non-funded opportunity where partners are expected to self-finance their participation, with a preference for exceptional U.S. entrepreneurial entities. Interested parties must submit a Technical Capability Summary Statement (TCSS) limited to six pages, along with a cover sheet and optional past performance appendix. Submissions are evaluated based on existing technical expertise, engineering development capacity, and financial ability. Due to the nature of the work, respondents must demonstrate the ability to handle controlled unclassified information or classified data, providing necessary facility and personnel clearance documentation. The submission deadline is October 15, 2026, at 1600 ET.

W6QK Acc-Apg Durham

POSTED

DEADLINE

SCO Offensive Fires - Solicitation

Solicitation # SCO-PS-26-11(12)

The Strategic Capabilities Office is seeking proposals for Project One and Project Two under solicitation number SCO-PS-26-11(12). This combined opportunity is managed by the Department of Defense and falls under NAICS code 541715, with the place of performance located in Chantilly, Virginia. Interested parties must submit their responses by the deadline of October 21, 2026. Due to the sensitive nature of the requirements, draft solicitations are only available via SECRET or higher level networks and will not be mailed. To request access, companies with the appropriate network capabilities must send an unclassified request to the SCO Offensive Fires Team at OffensiveFires@sco.mil, including a designated classified email address for delivery.

POSTED

DEADLINE

AI and Data Science Specialist Support – Health and Extreme Weather Project

Solicitation # 27-000165

The National Institutes of Health Clinical Center intends to procure specialized AI and Data Science Specialist support for the Health and Extreme Weather Intramural study. This two-year project focuses on how extreme heat impacts hospital overcrowding and mortality, specifically utilizing large language models and machine learning to extract critical patient data from unstructured Emergency Medical Services narratives. The scope of work includes technical consultation, AI prototyping, the development of scalable machine-learning pipelines, and the preparation of technical manuscripts and reports. The government intends to award this contract to the University of Maryland, College Park, Department of Electrical and Computer Engineering, citing their Ph.D.-level expertise and existing collaborative relationship with the NIH. The period of performance is divided into two one-year terms starting October 15, 2026. While the government has a preferred source, other responsible parties may submit capability statements demonstrating their expertise in healthcare AI and large-scale model evaluation by October 8, 2026.

National Institutes Of Health Olao

POSTED

DEADLINE

AIR CARGO DETECTION INNOVATION AND DEMONSTRATION BROAD AGENCY ANNOUNCEMENT

Solicitation # 70T04026BAA7573ACD

The Transportation Security Administration (TSA) has issued Broad Agency Announcement 70T04026BAA7573ACD to identify and demonstrate innovative air cargo detection, screening, mitigation, and resilience capabilities. The agency is seeking technologies, software, and algorithms that can improve security effectiveness and operational efficiency within TSA-regulated, industry-operated air cargo environments. To be considered, proposed solutions must be standalone and non-network-based due to security restrictions regarding sensitive TSA databases. The primary goal is to generate objective, measurable evidence through demonstrations in controlled or live environments to inform future acquisition strategies and policy decisions. Interested vendors must submit a white paper in one of three formats: a five-page document, a ten-slide deck, or a seven-minute video with a transcript. Submissions must include company information, a technical description, a Rough Order of Magnitude for demonstration costs, and a transition plan. There are three submission windows closing on January 15, 2027, May 15, 2027, and October 29, 2027, with all responses sent to TSA.Innovation@tsa.dhs.gov. TSA will evaluate submissions based on demonstration feasibility, evaluation quality, vendor capability, cost reasonableness, and transition potential. Selected vendors must provide a system for pre-demonstration assessment within 90 days of selection. The final procurement instrument may take the form of a bailment agreement, other transaction agreement, or memorandum of agreement.

Transportation Security Administration

POSTED

DEADLINE

in about 1 year

Intelligence Exploitation and Targeting Systems (IETS)

Solicitation # N6893626R5010

The Naval Air Warfare Center Weapons Division at China Lake, CA, is soliciting an Indefinite Delivery Indefinite Quantity (IDIQ) Multiple Award Contract (MAC) on a full and open competitive basis for the development, fielding, and sustainment of Intelligence Exploitation and Targeting Systems (IETS). This follow-on effort focuses on IETS derived from the Common Geo-Positioning (CGS) software package and related hardware used in the Distributed Common Ground System Navy (DCGS) family of programs. The solicitation, numbered N6893626R5010, is managed through the PIEE Solicitation Module, and all submissions must be received via that platform. Due to the nature of the work, contractors must be certified through Defense Logistics Information Services (DLIS) to access Controlled Unclassified Information (CUI) or Export Controlled Information. The scope of work includes software development and management activities, with key deliverables such as Software Design Descriptions, Interface Design Descriptions, and an Operations Security (OPSEC) Plan. Deliverables are governed by specific Data Item Descriptions (DIDs) and are submitted according to individual task orders. The government maintains a 30-day review period for data items, with contractors required to resubmit corrections within 15 days of receiving comments. Amendment 0001 extended the response deadline to October 8, 2026, and updated the RFP questions and responses. Offerors are required to provide comprehensive past performance data, business systems status checklists, and small business goal reports as part of their proposal submission.

Naval Air Warfare Center

POSTED

DEADLINE

ARMY OPEN SOLICITATION (AOS)

Solicitation # W9128Z-25-S-A002

The Army Open Solicitation (AOS), solicitation number W9128Z-25-S-A002, is an indefinite open solicitation issued by the U.S. Army Contracting Command-Aberdeen Proving Ground (ACC-APG) Digital Capability Contracting Center of Excellence. Its primary objective is to support all Army mission areas and maximize Army lethality by rapidly acquiring innovative commercial technologies, research and development solutions, and software acquisition pathway procurements. The AOS leverages a broad range of authorities, including FAR 6.102(d)(2), FAR 35.016 Broad Agency Announcements, and various 10 U.S.C. sections for prototypes and experimental procurements, as well as the Commercial Solutions Opening (CSO) process. Interested parties can engage through two primary methods: responding to Active Capability Gaps (ACG) or submitting proposals in response to specific Calls for Solutions. The award process generally follows a multi-phase approach consisting of a Solution Brief, a Live Pitch, and a final Solution Proposal. Evaluation is based on a hierarchy of Technical Merit, Viability, Feasibility and Desirability, and Schedule and Price. All submissions must be unclassified, and the government does not reimburse companies for costs incurred during the initial three phases of the solicitation process. Key administrative requirements include mandatory registration in the System for Award Management (SAM) and the use of the Wide Area Work Flow (WAWF) for invoicing. Security requirements mandate that all government data reside within the exclusive legal jurisdiction of the United States. Solution Briefs are strictly limited to five written pages in 12-point font or fifteen briefing slides and must be submitted as a single PDF document. While the overall AOS remains open in perpetuity until canceled, individual Calls for Solutions have specific, limited response windows.

W6QK Acc-Apg Contr Ctr

POSTED

DEADLINE

More opportunities from Department Of Health And Human Services → National Institutes Of Health

Same awarding agency

Early to Definitive Clinical Trials (R61/R33 Clinical Trial Required)The National Institutes of Health is forecasting a Notice of Funding Opportunity to solicit applications for early to definitive clinical trials. This initiative seeks proposals testing a wide range of interventions, including drugs, devices, biologics, procedures, and behavioral or social interventions, provided they align with the research missions of the participating NIH Institutes, Centers, and Offices. The funding will utilize a bi-phasic, milestone-driven R61/R33 activity code with a maximum project period of seven years. The R61 phase focuses on planning activities, while the R33 phase supports the actual clinical trial. Although applications are not currently being accepted, this notice serves as an advance alert for investigators with expertise in trial design, implementation, and stakeholder engagement to begin developing collaborations and projects.

POSTED

DEADLINE

Continuation of the Exceptional Longevity Data Management and Coordinating Center (EL DMCC) (U24 Clinical Trial Not Allowed)The National Institute on Aging intends to issue a single U24 cooperative agreement award to support the continued operation and expansion of the Exceptional Longevity Data Management and Coordinating Center. Serving as the central hub for human longevity translational research, the center integrates deeply phenotyped cohorts and multi-omics datasets to enable cross-cohort analyses and collaborative research. Key responsibilities include data harmonization, the implementation of common data standards, and the management of the ELITE Portal, which provides the research community with secure access to analytical tools and cloud-based computational workspaces. The upcoming funding opportunity will require the Coordinating Center to expand its capabilities in artificial intelligence, machine learning, and the integration of diverse datasets across different species. Future objectives include the development of curated target knowledgebases for therapeutic targets, the enhancement of portal interoperability according to FAIR data principles, and the strengthening of community engagement through specialized training and workshops. This notice serves as a forecast to allow potential applicants to establish collaborations before the official solicitation is released.

Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

DEADLINE

Immune Drivers of Autoimmune DiseaseThe National Institute of Allergy and Infectious Diseases seeks to support the Immune Drivers of Autoimmune Disease network to investigate the triggers and early mechanisms of autoimmunity in humans. The primary goal is to develop tools for risk prediction and staging, identify pre-clinical immune mechanisms, and utilize artificial intelligence and big data to prevent autoimmune diseases. This initiative emphasizes the creation of preclinical cohorts and the use of remote recruitment and sampling to advance medical research. The network will be managed by a Coordinating Center responsible for data harmonization, sample sharing, and the administration of an Infrastructure Opportunity Fund for collaborative research projects. This forecast, issued by the National Institutes of Health under the Department of Health and Human Services, establishes a framework for shared infrastructure and steering committee oversight to identify common pathways and prevention opportunities.

Research and Development in Biotechnology (except Nanobiotechnology)

POSTED

DEADLINE

NLM Grants for Scholarly Works in Biomedicine and Health (G13 Clinical Trial Not Allowed)The National Institutes of Health, through the Department of Health and Human Services, is soliciting applications for the NLM Grants for Scholarly Works in Biomedicine and Health program. This initiative provides funding for the creation of book-length manuscripts and other integrative scholarly works, such as critical reviews and analytical syntheses, designed to benefit U.S. health professionals, scientists, and public health practitioners. The primary goal is to organize and disseminate biomedical and health-related knowledge to improve research, education, and clinical practice. This opportunity is listed as a forecast with a posted date of September 24, 2026. It specifically prohibits the use of clinical trials. Interested parties can contact the NLM Extramural Programs office for further information regarding the application process and program requirements.

Book Publishers

POSTED

DEADLINE

Partnerships for Advancing Development of Diagnostics for Infectious DiseasesThe National Institute of Allergy and Infectious Diseases, under the National Institutes of Health, is seeking to establish partnerships between academic or small business investigators and industrial partners to advance the translational development of diagnostic tests for infectious diseases. This initiative focuses on moving diagnostics that have already demonstrated proof-of-concept through the commercialization process by aligning researchers with experienced industry partners to de-risk development and ensure products are fit for purpose. The program will be supported by a science advisory board and NIAID oversight, incorporating annual meetings and workshops to facilitate collaboration and knowledge exchange. This effort is authorized under the Public Health Service Act and federal regulations to ensure that promising diagnostic technologies are successfully translated into tools for treating and preventing infectious diseases.

Research and Development in Biotechnology (except Nanobiotechnology)

POSTED

DEADLINE

LeverAging StraTegies to Maximize ImpLementation and Effectiveness for HIV (LAST MILE)The National Institute of Allergy and Infectious Diseases, under the Department of Health and Human Services, is forecasting the LeverAging StraTegies to Maximize ImpLementation and Effectiveness for HIV (LAST MILE) program. This initiative aims to bridge the gap between traditional clinical trial findings and real-world application by supporting collaborations on effectiveness trials, pragmatic trials, and hybrid effectiveness-implementation studies. The program focuses on the prevention and treatment of HIV, including associated coinfections and comorbidities, across all age groups and various points of care. The goal of the program is to advance cross-cutting research in epidemiology, implementation science, and clinical, behavioral, and social sciences. This effort aligns with the broader NIH mission to implement research advances in HIV/AIDS. The opportunity is authorized under the Public Health Service Act and relevant federal regulations, with administrative oversight provided by the Division of AIDS Epidemiology Branch.

Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

DEADLINE

Collaborative Centers in Children’s Environmental Health Research and Translation (P2C Clinical Trial Optional)The National Institutes of Health, under the Department of Health and Human Services, is seeking applications to establish a national network of Children's Environmental Health Research Translation Centers. These centers are designed to protect and improve children's health by developing scientific questions and public health interventions focused on translational research. A primary objective is to move evidence-informed biomedical findings into practical application for the wider community while mentoring a new generation of investigators in the field. Beyond research and translation, the program will function as a national resource to coordinate responses to emerging environmental exposures that impact children. The initiative emphasizes the creation of actionable strategies to prevent harm and ensure a healthy future for children through collaborative efforts within the environmental health community.

Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

DEADLINE

The Role of the Innate Immune System in the Pathogenesis of Type 1 DiabetesThe National Institute of Allergy and Infectious Diseases, under the Department of Health and Human Services, is forecasting a grant opportunity to investigate the role of the innate immune system in the initiation of Type 1 Diabetes. Funded by the Special Statutory Funding Program for Type 1 Diabetes Research, this initiative seeks to identify genetic and environmental causes of the disease by examining how innate immune components interact with beta cells and pancreatic tissues. The program emphasizes the use of new approach methodologies to determine the timing and impact of environmental triggers that activate these immune pathways. The primary objective is to improve the early identification of high-risk individuals and develop future prevention and therapeutic strategies. This effort is conducted under the authority of the Public Health Service Act and relevant federal regulations. Interested parties can contact the RISP-T1D point of contact for further information regarding this forecast.

Research and Development in Biotechnology (except Nanobiotechnology)

POSTED

DEADLINE

Amyotrophic Lateral Sclerosis (ALS) Intermediate Patient Population Expanded Access (U01 Clinical Trial Required)The National Institute of Neurological Disorders and Stroke (NINDS) is seeking to support scientific research using data from intermediate-size patient population expanded access protocols for Amyotrophic Lateral Sclerosis (ALS). To be eligible, protocols must provide access to an investigational drug or biological product for individuals with ALS and generate data that supports research into the prevention, diagnosis, mitigation, treatment, or cure of the disease. Research goals may include analyzing the effects of products on biomarkers, target engagement, safety and outcome information such as survival and hospitalization, or general patient experience data. This opportunity is currently listed as a forecast by the National Institutes of Health under the Department of Health and Human Services, and applications are not being solicited at this time. The notice serves as a preliminary announcement to allow potential applicants sufficient time to develop responsive projects. Interested parties can contact the ALS Program for further information.

Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

DEADLINE

Research to Improve Rigor, Replicability, and Reproducibility in Biomedical and Behavioral SciencesThe National Institute of Neurological Disorders and Stroke, in collaboration with other NIH entities, is forecasting support for research projects aimed at enhancing biomedical and behavioral rigor, replicability, and reproducibility. Key areas of interest include assessing the scientific impact of these improvements, creating frameworks for selecting high-value replication studies, and measuring the robustness and generalizability of research findings to drive scientific innovation. This notice serves as a forecast to allow potential applicants to establish collaborations and develop responsive projects, as formal applications are not currently being solicited. Interested parties can contact the NINDS Office of Research Quality for further information.

Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

DEADLINE

Advancing Real-World Effectiveness Evidence for Rapid-Acting Psychotropic Interventional Drugs (RAPIDs)The National Institutes of Health, through the National Institute of Mental Health, is issuing a forecast for a Notice of Funding Opportunity titled Advancing Real-World Effectiveness Evidence for Rapid-Acting Psychotropic Interventional Drugs (RAPIDs). This initiative aims to establish a research network to evaluate the clinical effectiveness, safety, and durability of rapid-acting treatments such as ketamine, esketamine, and psilocybin for individuals with serious mental illnesses. The primary objective is to generate actionable real-world evidence to determine how these interventions can be safely and sustainably integrated into routine clinical practice across diverse patient populations and healthcare settings. By addressing current gaps in knowledge regarding implementation and long-term benefits, the project seeks to inform future healthcare delivery strategies for emerging psychotropic treatments.

Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

DEADLINE

Emerging Global Leader Award (K43)The Emerging Global Leader Award (K43), issued by the National Institutes of Health under the Department of Health and Human Services, provides salary and research support to junior faculty and research scientists based at academic or research institutions in Low- and Middle-Income Countries. The program focuses on biomedical, behavioral, and clinical research that leverages unique opportunities in these regions to create generalizable knowledge benefiting both U.S. and international populations. Recipients must engage in intensive mentored research and career development guided by senior researchers from both the U.S. and their respective home countries. By leveraging existing NIH research investments, the initiative aims to develop global research leaders who can mentor future investigators and strengthen international research networks.

Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

DEADLINE

Ready to Pursue This Opportunity?

Get AI-powered intelligence on this solicitation and the ones like it

Every page of the solicitation package shredded into a compliance breakdown

AI-powered matching based on your capabilities and past performance

Competitor and incumbent history on the requirement

Automated alerts on amendments, Q&A deadlines, and award

Join 750+ contractors already using CLEATUS