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Forecast to Publish a Funding Opportunity Announcement for Advanced Development of Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)

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The National Cancer Institute, under the Department of Health and Human Services, is issuing a Notice of Funding Opportunity under solicitation RFA-CA-27-020 to support the advanced development and enhancement of emerging informatics technologies. This initiative, part of the Informatics Technology for Cancer Research Program, targets technologies that have moved beyond initial prototyping and pilot stages but have not yet been widely adopted. The goal is to improve the acquisition, analysis, visualization, and interpretation of data across the entire cancer research continuum, including cancer biology, diagnosis, treatment, early detection, risk assessment, and health disparities. Successful applications must utilize the U24 activity code and demonstrate a clear rationale for the technology's necessity and its potential to provide significant advantages over competing tools. Projects must include comprehensive plans for engaging end users, soliciting feedback from the research community, and implementing outreach and training to ensure broad adoption. Applicants are required to provide realistic timelines and milestones for development. This opportunity is designed for investigators with expertise in cancer informatics to create user-friendly tools that support discovery biology, population studies, and clinical or translational research.

General Info

NCI funding for advanced cancer informatics technologies to improve data analysis and adoption.

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health
Contacts1 person available
OfficeUSA
Office AddressUSA
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Juli Klemm PhD National Cancer Institute

Full Description

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The National Cancer Institute intends to publish a Notice of Funding Opportunity (NOFO) to invite applications for advanced development and enhancement of emerging informatics technologies to improve the acquisition, analysis, visualization, and interpretation of data across the cancer research continuum including cancer biology, cancer treatment and diagnosis, early cancer detection, risk assessment and prevention, cancer control and epidemiology, and cancer health disparities. As a component of the NCI's Informatics Technology for Cancer Research (ITCR) Program, this NOFO will focus on advancing emerging informatics technology, defined as one that has passed the initial prototyping and pilot development stage, has demonstrated potential to have a significant and broader impact, has compelling reasons for further improvement and enhancement, and has not been widely adopted in the cancer research field. To be successful, proposed development plans must have a clear rationale for why the proposed technology is needed and how it will benefit the cancer research field. In addition, mechanisms to solicit feedback from driving cancer research projects as well as the broader user community throughout the development process must be included.


This NOFO will invite applications for the enhancement and dissemination of emerging, user-friendly informatics technologies that support a wide range of cancer research, including discovery biology, population studies, as well as clinical and translational research. The emphasis will be on uniqueness and potential impact on cancer research. In addition, all projects proposed in response to this NOFO must involve the following general attributes:


  • Potential to advance driving cancer research projects and the cancer research field in general;
  • Offers clear advantages over competing technologies in the targeted cancer research domain;
  • Provides compelling plans and processes for supporting and engaging end users to evaluate and apply the tool or resource;
  • Provides plans for advancing use of the tool or resource by the targeted community through collaboration, outreach, and training;
  • Provides a realistic timeline and milestones for technology development.


Applications are not being solicited at this time. This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the U24 activity code. Investigators with expertise and insights into cancer informatics are encouraged to begin to consider applying for this NOFO. 

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