Forecast to Publish a Funding Opportunity Announcement for Sustained Support for Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)
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The National Cancer Institute, under the Department of Health and Human Services, is issuing a funding opportunity announcement under solicitation RFA-CA-27-021 to provide sustained support for high-value informatics research resources. Utilizing the U24 activity code, this initiative focuses on the continued development, maintenance, and evolution of widely adopted informatics tools that improve the acquisition, management, analysis, and dissemination of data across the cancer research continuum. This includes areas such as cancer biology, treatment, diagnosis, early detection, risk assessment, prevention, epidemiology, and health disparities. Unlike early-stage development efforts, this program specifically targets the sustainment of existing resources that have already demonstrated a significant impact on the cancer research field. To be successful, applicants must provide a clear justification for the resource's maintenance and demonstrate how it has benefited and will continue to benefit the research community. Proposals must include robust plans for end-user support, including comprehensive documentation, training, and outreach activities. Additionally, applicants must outline clear processes for engaging with the research community to address emerging needs and ensure the resource remains scientifically relevant. This opportunity is designed to support a wide range of research, including discovery biology, population studies, and clinical and translational research, with a strong emphasis on maximizing the value of the resource to the targeted research community.
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Full Description
The National Cancer Institute intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for the continued development and sustainment of high value informatics research resources to improve the acquisition, management, analysis, and dissemination of data and knowledge across the cancer research continuum including cancer biology, cancer treatment and diagnosis, early cancer detection, risk assessment and prevention, cancer control and epidemiology, and/or cancer health disparities. As a component of the NCI's Informatics Technology for Cancer Research (ITCR) Program, this NOFO will focus on sustaining operations and maintaining and evolving the scientific relevance of existing, widely-adopted informatics tools and resources. This is in contrast to early-stage and advanced development efforts to generate these tools and resources that will be supported by companion ITCR NOFOs. The central mission of ITCR is to promote research-driven informatics technology across the development lifecycle to address priority needs in cancer research. In order to be successful, the application must provide clear justification for why the research resource should be maintained and how it has benefited and will continue to benefit the cancer research field. In addition, mechanisms for assessing and maximizing the value of the resource to researchers and supporting close engagement between the resource and the targeted research community should be described.
This NOFO invites applications to support the sustained operations of informatics technology resources that support a wide range of cancer research, including discovery biology, population studies, as well as clinical and translational research. The emphasis will be on sustaining resources that have had a demonstrated impact on cancer research. In addition, all projects proposed in response to this NOFO must involve the following general attributes:
- Evidence that the technology has had significant impact on cancer research to date and the sustainment plan will lead to the continued advancement of cancer research
- Robust plans for supporting the end-user community including documentation, training, and other outreach activities
- Clear processes for engaging end users to address emerging needs of the targeted research communities to ensure that the research resource maintains relevance to the research it supports
Applications are not being solicited at this time. This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the U24 activity code. Investigators with expertise and insights into cancer informatics are encouraged to begin to consider applying for this NOFO.
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