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Collaborative Awards to Support Microphysiological System Pilot Studies in Type 2 Diabetes Research

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Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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The National Institute of Diabetes and Digestive and Kidney Diseases plans to release a Notice of Funding Opportunity to support pilot research studies using microphysiological systems (MPSs) aimed at modeling type 2 diabetes. These advanced MPSs leverage biomaterials, microfluidics, and tissue engineering to create sophisticated three-dimensional cell cultures that accurately replicate human tissue environments. This technology enables detailed investigation into metabolic tissue interactions, fundamental mechanisms underlying type 2 diabetes, and the evaluation of potential prevention and treatment approaches. The initiative specifically targets small-scale, exploratory studies designed to assess the feasibility of using MPSs in this context and to generate preliminary data for further research. Although applications are not currently being accepted, this advance notice serves to give researchers ample time to form collaborations and develop responsive projects. The funding opportunity encourages interdisciplinary partnerships that bring together expertise in bioengineering, diabetes biology, and human metabolism. This collaborative approach is intended to foster innovative research that addresses the complexity and heterogeneity of type 2 diabetes, ultimately advancing the understanding of disease biology and improving clinical interventions. Interested investigators are advised to prepare now in anticipation of the forthcoming solicitation.

General Info

Funding opportunity for pilot studies using microphysiological systems to model type 2 diabetes.

Agency

Department Of Health And Human Services → National Institutes Of Health

NAICS

541714 - Research and Development in Biotechnology (except Nanobiotechnology)View NAICS

Place of Performance

Not specified

Set-Aside

NONE

Documents

(0)

No documents available

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health
Contacts1 person available
OfficeUS
Organization / Agency
Department Of Health And Human Services → National Institutes Of Health
Office AddressUS
Contacts
Albert J. Hwa PhD
contact@example.gov
+1 (555) 000-0000

Full Description

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The National Institute of Diabetes and Digestive and Kidney Diseases intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for research on microphysiological systems (MPSs) to model type 2 diabetes. Advances in biomaterials, microfluidics, and tissue engineering have resulted in MPSs that allow for greater control of three-dimensional cell cultures containing multiple cell types and constituting more physiological tissue organization. The utility of these systems lends themselves to powerful in vitro modeling of metabolic tissue crosstalk, study of basic mechanisms of human type 2 diabetes, and the testing of prevention and treatment strategies. MPSs are especially useful for investigating the heterogeneity of human T2D biology and clinical responses. The current initiative will support small pilot studies to conceptualize aspects of T2D biology for modeling with MPSs, to support feasibility studies, and to generate preliminary data. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. Collaborative investigations combining expertise in bioengineering, type 2 diabetes biology, and human metabolism will be encouraged and these investigators should begin considering applying for this application. 

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