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GREGoRi Technology Integration Center (U01, Clinical Trials Optional)

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Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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The National Institutes of Health, through the National Human Genome Research Institute, is issuing solicitation RFA-HG-27-012 to establish the GREGoRi Technology Integration Center. This initiative, a renewal of the Genomics Research to Elucidate the Genetics of Rare Disease program, aims to accelerate a paradigm shift in rare disease diagnosis by developing new tools, molecular technologies, and analytical approaches to identify causal genes and variants. The center will focus on creating standards and best practices for emerging molecular methods and producing a multidimensional dataset for benchmarking novel diagnostic strategies. This opportunity utilizes the U01 activity code and allows for optional clinical trials. The solicitation was posted on June 6, 2025, with an application deadline of October 30, 2026. Managed under NAICS code 541714, the program is designed to foster meaningful collaborations to improve the identification of rare genetic disorders.

General Info

NIH RFA-HG-27-012 establishes GREGoRi Center to improve rare disease genetic diagnosis tools.

Agency

Department Of Health And Human Services → National Institutes Of Health

NAICS

541714 - Research and Development in Biotechnology (except Nanobiotechnology)

Place of Performance

Not specified

Set-Aside

NONE

Documents

0

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Documents will appear here when they are available.

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health
Contacts1 person available
OfficeUSA
Organization / AgencyDepartment Of Health And Human Services → National Institutes Of Health
Office AddressUSA
Contacts
Lisa H. Chadwick National Human Genome Research Institute (NHGRI
contact@example.gov
+1 (555) 000-0000

Full Description

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The National Human Genome Research Institute (NHGRI) intends to promote a new initiative by publishing a Notice of Funding Opportunity (NOFO) to renew the Genomics Research to Elucidate the Genetics of Rare Disease (GREGoR) program. The renewal, called GREGoR: Innovation (GREGoRi), seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular technologies and analytical approaches used to identify the causal gene(s) and/or variant(s) underlying rare genetic disorders. The purpose of this NOFO is to establish the GREGoRi Technology Integration Center (TechIC), which will enable the development of standards and best practices for applying new and emerging molecular methods in rare disease diagnosis. A major deliverable of the Center will be a multidimensional dataset that can be used for the development and benchmarking of novel tools and strategies that facilitate rare disease diagnosis.


This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. The NOFO is expected to be published in 2025 with an expected application due date in 2026. This NOFO will utilize the U01 activity code.

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