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Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Therapeutic Agent Characterization and Preclinical Efficacy Studies

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Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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The National Institutes of Health, specifically the National Institute of Neurological Disorders and Stroke, National Institute of Aging, and the NIH Helping to End Addiction Long Term (HEAL) initiative, along with participating institutes, are supporting projects aimed at conducting pharmacodynamic, pharmacokinetic, and efficacy studies of therapeutic agents. These studies focus on demonstrating the biological activity of small molecules or biologics to justify their continued development as treatments for various disorders or diseases relevant to the participating agencies. The initiative also emphasizes the development of non-opioid analgesic therapeutics with minimal addiction potential. Efficacy testing can be performed using validated in vivo models or New Approach Methodologies (NAMs), ensuring scientific rigor in evaluating therapeutic potential. At this stage, applications are not open; rather, this notification is designed to give prospective applicants ample time to establish collaborations and prepare responsive, well-developed projects. This effort is part of the Innovation Grants to Nurture Initial Translational Efforts (IGNITE) program, which aims to advance early translational research by characterizing potential therapeutic agents and conducting preclinical efficacy studies. Interested parties can reach out for more information or future application opportunities through the designated NIH contact email.

General Info

NIH IGNITE program supports early translational studies of non-opioid therapeutics’ biological activity.

Agency

Department Of Health And Human Services → National Institutes Of Health

NAICS

541714 - Research and Development in Biotechnology (except Nanobiotechnology)View NAICS

Place of Performance

Not specified

Set-Aside

NONE

Documents

(0)

No documents available

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health
Contacts1 person available
OfficeUS
Organization / Agency
Department Of Health And Human Services → National Institutes Of Health
Office AddressUS
Contacts
contact@example.gov

Full Description

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The National Institute of Neurological Disorders and Stroke, National Institute of Aging, the NIH Helping to End Addiction Long Term (HEAL) initiative, and other participating ICs seek to support applications to conduct pharmacodynamic, pharmacokinetic, and efficacy studies to demonstrate that the proposed therapeutic agent(s) have sufficient biological activity to warrant further development as therapeutics for disorders or diseases supported by participating ICs or for non-opioid analgesic therapeutics with little or no addiction liability as a part of the NIH HEAL initiative. Therapeutic agents include small molecules or biologics. Efficacy testing can be conducted in validated in vivo models and/or validated New Approach Methodologies (NAMs) as appropriate.

Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects.

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