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Single Source Competition: Continuation of the Cardiovascular Repository for Type 1 Diabetes (CaRe-T1D) - Resource Center (U24 Clinical Trial Not Allowed)

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The contract aims to continue supporting the Cardiovascular Repository for Type 1 Diabetes (CARE-T1D) consortium, originally established to collect and analyze cardiovascular tissues from organ donors with type 1 diabetes, type 2 diabetes, and no diabetes. This resource center focuses on advancing research into the pathogenesis of cardiac disease in type 1 diabetes by utilizing multi-omics and molecular approaches. The goal is to maintain and expand the biorepository and associated data, enhance consortium coordination, and facilitate sharing of cardiovascular tissue samples and research findings. This research is intended to deepen understanding of cardiovascular disease in type 1 diabetes compared to type 2 diabetes and non-diabetic populations, with the ultimate objective of developing targeted therapies to address this leading cause of mortality among people with type 1 diabetes. This opportunity is a single source competition expected to invite applications from eligible organizations. Applicants will undergo the NIH's standard peer-review processes, and only the most meritorious proposals will be considered for funding. The contract is managed by the National Institutes of Health under the Department of Health and Human Services, with points of contact available to provide additional information. The project prohibits clinical trials under this resource center funding mechanism.

General Info

Continue supporting CARE-T1D biorepository, advancing cardiovascular disease research in type 1 diabetes.

Agency

Department Of Health And Human Services → National Institutes Of Health

NAICS

541714 - Research and Development in Biotechnology (except Nanobiotechnology)View NAICS

Place of Performance

Not specified

Set-Aside

NONE

Documents

(0)

No documents available

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health
Contacts1 person available
OfficeUS
Organization / Agency
Department Of Health And Human Services → National Institutes Of Health
Office AddressUS
Contacts
Teresa L. Z. Jones
contact@example.gov
+1 (555) 000-0000

Full Description

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The NIDDK and NHLBI seek to advance their mission by a continuation of the Cardiovascular Repository for Type 1 Diabetes (CARE-T1D) consortium. The CARE-T1D biorepository was established in 2020 through RFA-DK-21-010 and has successfully collected, stored and analyzed cardiovascular tissue (hearts, aortas, carotid arteries and kidneys) from organ donors with type 1 diabetes, type 2 diabetes and without diabetes. A consortium was formed in 2024 through RFA-DK-23-021 to carry out research focused on hypothesis driven research on pathogenesis of cardiac disease in T1D using multi-omics and molecular approaches using the CARE-T1D resources. The goal of this funding opportunity is to continue the CARE-T1D resource center and its work in collecting, analyzing and sharing cardiovascular tissue from organ donors with type 1 diabetes, type 2 diabetes and without diabetes; maintaining and expanding the data repository with results from the consortium resources; and coordinating consortium activities.  This research seeks to improve our understanding of cardiovascular disease in type 1 diabetes and the differences with type 2 diabetes and no diabetes to develop therapies to treat this major cause of mortality for people with type 1 diabetes. 

This is a Forecast for a Single Source competition that will invite application(s) from eligible organization(s) to apply. Please see Eligibility Section for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding.

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