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Translational Centers Using Microphysiologic Systems for Infectious Diseases

Forecast
RFA-AI-28-012Grant

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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The National Institute of Allergy and Infectious Diseases, under the Department of Health and Human Services, is forecasting an opportunity to support the development of human microphysiologic systems for infectious disease research and the creation of therapeutics or biological products. These in vitro platforms are designed to mimic human physiological processes and organ functions, aiming to reduce reliance on animal testing and establish human tissue models that are acceptable to regulatory bodies like the FDA. The program focuses on accelerating the adoption of these systems by drug and biological product developers to enhance basic research and product development. This initiative is authorized under the Public Health Service Act and relevant federal regulations, with administrative oversight provided by the Division of Microbiology and Infectious Diseases.

General Info

Funding for translational microphysiologic systems to advance infectious disease research and therapeutic development.

Agency

Department Of Health And Human Services → National Institutes Of Health

NAICS

541714 - Research and Development in Biotechnology (except Nanobiotechnology)

Place of Performance

Not specified

Set-Aside

NONE

Documents

0

No documents available

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Timeline

PhaseForecast
Posted

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health
Contacts1 person available
OfficeUSA
Organization / AgencyDepartment Of Health And Human Services → National Institutes Of Health
Office AddressUSA
Contacts
Division of Microbiology and Infectious Diseases (DMID) MPSTranslational
contact@example.gov

Full Description

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The National Institute of Allergy and Infectious Diseases (NIAID) seeks to advance its mission by supporting the development of human microphysiologic systems (MPS) for infectious disease research and the development of therapeutics or biological products. MPS are in vitro platforms composed of cells or tissues maintained in a microenvironment designed to mimic the physiological aspects of in vivo tissue or organ function. There is growing support for the development of MPS for basic research at NIH and regulatory pathways at the FDA with the aim of reducing the use of animals in research and generating human tissue models that can be used to study human physiological processes. However, MPS development has not focused on their use in studies of infectious diseases or for product development. The goal of this program is to accelerate the use of MPS for infectious diseases and product development, promoting adoption for use by developers of drugs and biological products and their regulatory acceptance. Grant authorities that allow NIAID to forecast this opportunity are as follows: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200. 

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